Cementless Hip Arthroplasty in Paget's Disease at Medium-Term Follow-Up (Average of 6.7 Years)

Lusty, P.J.; Walter, William L.; Walter, William K.; Zicat, B.

doi:10.1016/j.arth.2006.09.010

Cited by 29 publications

(21 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results are in agreement with previously reported series [1,11,14,17,27] and close to those described in cementless hydroxyapatite fully coated THAs implanted in patients without PDB [3,7,8,34]. The control of PDB activity in the pre-operative period reduces the risk of implant loosening and the abnormal intra-operative blood loss.…”

Section: Discussionsupporting

confidence: 83%

“…To our knowledge, the largest previous series included 33 hips with a 6.7-year average follow-up [17]. However, our study has some limitations.…”

Section: Discussionmentioning

confidence: 81%

“…In recent years, the use of uncemented components in PDB has been proposed and reported with promising results with regard to the mid-term outcome and fixation [1,11,14,17,27]. However, the benefits from the use of uncemented components remain unclear as active PDB may compromise the fixation and altered quality and morphological features of pagetic bone may influence bone ingrowth into cementless implants.…”

Section: Discussionmentioning

confidence: 99%

“…The average age at surgery was 74.2 years (range 55-89) and the average time to diagnosis of PDB was 13.1 years (range 1-36). The average body mass index was 25 kg/m² (range [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]. The 39 procedures included 37 primary replacements and two revision procedures.…”

Section: Methodsmentioning

confidence: 99%

“…Recently, the use of cementless implants in patients with PDB has been reported with encouraging results [1,11,14,17,27].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Cementless total hip arthroplasty in Paget’s disease of bone: a retrospective review

Wegrzyn¹,

Pibarot²,

Chapurlat³

et al. 2009

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

Paget's disease of bone (PDB) is a localised chronic osteopathy leading to bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. The pelvis and upper femur are frequently involved, resulting in disabling hip disease, and total hip arthroplasty (THA) may be required. We performed a retrospective study on the management and the outcome of 39 uncemented hydroxyapatite fully-coated THA in patients with PDB of the hip. The follow-up averaged 79.4 months (range 24-194). Functional scores improved significantly and, using the Harris hip score, 84% of patients had an excellent clinical outcome at the latest follow-up. Despite one case of an uncemented acetabular component with probable loosening, no implant revision had been required at our latest follow-up. Signs of implant loosening were found to be significantly more frequent in patients with active disease. For this reason, we advocate the use of pre-operative medication with bisphosphonates to reduce disease activity. Another benefit of this treatment is the significant decrease of intra-operative blood loss. Provided the control of disease activity in the pre-operative period with bisphosphonates is achieved, good outcome of cementless THAs can be expected. Bisphosphonates reduced the risk of implant loosening and excessive intra-operative blood loss

show abstract