Abstract:The current work was devoted to study the solidification of bioproducts originated from the bioremediation of mixture of solid cellulose-based radioactive waste simulates using a mushroom (Pleurotus pulmonarius), in Portland cement. The obtained solidified waste form was subjected to mechanical integrity qualification after curing periods of 28 and 90 days. Chemical performance of the cement-waste form was also evaluated in different leachant media during 540 days. The results obtained gave useful information … Show more
“…Pleurotus pulmonarius is identified as an effective fungus in degrading crude oil, offering a natural solution to oil spill remediation efforts [65]. Moreover, the efficacy of Pleurotus pulmonarius is successfully confirmed in combating radioactive cellulosebased waste, signifying its worth in nuclear waste management [66]. Spent Mushroom Compost (SMC) has arisen as a treasured resource in myco-remediation, with studies by Law et al revealing the capacity of Pleurotus pulmonarius SMC to significantly reduce pentachlorophenol (PCP) levels [67].…”
Mushrooms have become gradually prominent in modern diets, with a surge in consumption across a diverse array of species. Among these, the genus Pleurotus, colloquially known as "Oyster mushrooms", stands out, boasting nearly 40 distinct species. Pleurotus ostreatus (P. ostreatus), in particular, relishes widespread popularity globally due to its mouth-watering taste, appealing flavor profile, and remarkable nutritional profile. Well-known for its abundance of indispensable nutrients and bioactive compounds, P. ostreatus has been the subject of extensive research highlighting its many-sided medicinal properties. Studies have projected its potential as an antidiabetic, antibacterial, anticholesterol, antiarthritic, antioxidant, anticancer, and antiviral agent, concomitant with encouraging eye health. This review underscores the remarkable nutritional richness of P. ostreatus and delves into its profound implications for medicinal applications, positioning these mushrooms as indispensable nutraceutical functional foods with vast therapeutic potential.
“…Pleurotus pulmonarius is identified as an effective fungus in degrading crude oil, offering a natural solution to oil spill remediation efforts [65]. Moreover, the efficacy of Pleurotus pulmonarius is successfully confirmed in combating radioactive cellulosebased waste, signifying its worth in nuclear waste management [66]. Spent Mushroom Compost (SMC) has arisen as a treasured resource in myco-remediation, with studies by Law et al revealing the capacity of Pleurotus pulmonarius SMC to significantly reduce pentachlorophenol (PCP) levels [67].…”
Mushrooms have become gradually prominent in modern diets, with a surge in consumption across a diverse array of species. Among these, the genus Pleurotus, colloquially known as "Oyster mushrooms", stands out, boasting nearly 40 distinct species. Pleurotus ostreatus (P. ostreatus), in particular, relishes widespread popularity globally due to its mouth-watering taste, appealing flavor profile, and remarkable nutritional profile. Well-known for its abundance of indispensable nutrients and bioactive compounds, P. ostreatus has been the subject of extensive research highlighting its many-sided medicinal properties. Studies have projected its potential as an antidiabetic, antibacterial, anticholesterol, antiarthritic, antioxidant, anticancer, and antiviral agent, concomitant with encouraging eye health. This review underscores the remarkable nutritional richness of P. ostreatus and delves into its profound implications for medicinal applications, positioning these mushrooms as indispensable nutraceutical functional foods with vast therapeutic potential.
“…Hydrophilic, nontoxic, stable, and biodegradable characterize each of these polymers in nature 39 . It is the process by which a material is broken down into its constituent parts by the activity of microorganisms, such as bacteria, in a biochemical reaction 40 . Biodeterioration, bio fragmentation, and assimilation are the three primary steps of the biodegradation mechanism 41 .…”
A hydrogel with strongly cross-linked hydrophilic polymer chains makes up the majority of nanogels, which are essentially nanoparticles. Several hydrophilic functional groups in hydrophilic polymers enable nanogels to absorb large amounts of water. Incredibly stable, adaptable, and responsive to sensory influences, nanogels have the potential to be a safe and effective medication delivery vehicle for biological products. Peptides, hormones, DNA, vaccines, chemotherapeutic treatments, and a wide range of pharmaceutical goods can all be delivered using these devices. There are several varieties of nanogel-based drug delivery systems, varied techniques of production, processes of drug release, and commercially available formulations. The presentation emphasizes the various types of nanogel based drug delivery systems, preparation methods, drug release mechanisms, marketed preparations, and their various applications in the medical field.
INTRODUCTION:Nanotechnology has been extensively used in the construction of innovative drug delivery systems because it provides acceptable strategies for the time-specific or timecontrolled administration of bioactive substances. Because of the nanoscale size's capacity to improve drug dispersion, increase tumor accumulation, increase stability against chemical and enzymatic degradation and reduce cytotoxic side effects during cancer treatment, the nanoscale size can be advantageous in drug delivery 1 . Aqueous dispersions of hydrogel particles generated by
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“…All these polymers are hydrophilic, non-toxic, stable and biodegradable in nature [51]. Biodegradation is the conversion of a substance into new products by biochemical reactions or the actions of microorganisms such as bacteria [52].…”
Section: Biocompatibility and Degradabilitymentioning
Nanogels have attracted considerable attention as nanoscopic drug carriers, particularly for site-specific or time-controlled delivery of bioactive mediators. A high diversity of polymer systems and the simple modification of their physicochemical features have provided multipurpose forms of nanogel preparations. Nanogels have outstandingly high stability, drug loading ability, biologic consistence, good permeation capability and can be responsive to environmental stimuli. Great potential has been shown by nanogels in many fields including delivery of genes, chemotherapy drugs, diagnosis, targeting of specific organs and several others. This review focuses mainly on different types of nanogels, methods of preparation including methods of drug loading, different modes of biodegradation mechanisms as well as main mechanisms of drug release from nanogels. Recent applications of nanogels are also briefly discussed and exemplified.
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