Cellulose gum and copper nanoparticles based hydrogel as antimicrobial agents against urinary tract infection (UTI) pathogens

Al-Enizi, Abdullah M.; Ahamad, Tansir; Al-hajji, Abdullah Baker; Ahmed, Jahangeer; Chaudhary, Anis Ahmad; Alshehri, Saad M.

doi:10.1016/j.ijbiomac.2017.11.057

Cited by 47 publications

(25 citation statements)

References 47 publications

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“…To measure HCuNPs and hydrogel antibacterial activity, they applied the agar disc diffusion method. The results indicated that HCuNPs had a superior biocidal activity than parenteral hydrogel in similar conditions giving a ZOIs higher than 16 mm for all the pathogens at a concentration of 5 mg/mL (Al-Enizi et al, 2018).…”

Section: Use Of Composite Materialsmentioning

confidence: 95%

“…Also, Lim et al, suggested the use of Ag-PL-NPs by direct inoculation intro de bladder, a tendency shown in other investigators with organic and inorganic NPs, due the advantage that local administration represent (Lim et al, 2015). Interestingly, A-Enizi et al, described an innovative application for their HcuNPs, given their great antimicrobial and absorption properties, suggesting their use in diapers, sanitary towels, menstrual pads, and related products (Al-Enizi et al, 2018).…”

Section: Use Of Composite Materialsmentioning

confidence: 99%

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Nanoparticles as Potential Novel Therapies for Urinary Tract Infections

Sánchez

Navarro

Catalán-Figueroa

et al. 2021

Front. Cell. Infect. Microbiol.

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Urinary tract infection (UTI) is one of the most common reasons for antibiotic treatment. Nevertheless, uropathogens are steadily becoming resistant to currently available therapies. In this context, nanotechnology emerges as an innovative and promising approach among diverse strategies currently under development. In this review we deeply discuss different nanoparticles (NPs) used in UTI treatment, including organic NPs, nanodiamonds, chemical and green synthesized inorganic NPs, and NPs made of composite materials. In addition, we compare the effects of different NPs against uropathogens in vivo and in vitro and discuss their potential impact the in the near future.

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Section: Use Of Composite Materialsmentioning

confidence: 95%

Section: Use Of Composite Materialsmentioning

confidence: 99%

Nanoparticles as Potential Novel Therapies for Urinary Tract Infections

Sánchez

Navarro

Catalán-Figueroa

et al. 2021

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

show abstract

“…Due to the redox-active properties of copper, several groups employed copper-based NPs for their activity against UTIs. In this regard, Al-Enizi et al [136] formulated a copper NP-based hydrogel matrix, with a particle size distribution of 7-12 nm. The antimicrobial and cytotoxic activities of the formulation were evaluated in UTI microbes (Escherichia coli, Klebsiella pnemoniae, Pseudomonas aeruginosa, Proteus vulgaris, Staphylococcus aureus, Proteus mirabilis) and HeLa cell lines.…”

Section: Copper Npsmentioning

confidence: 99%

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections

et al. 2021

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The diagnosis and treatment of urinary tract infections (UTIs) remain challenging due to the lack of convenient assessment techniques and to the resistance to conventional antimicrobial therapy, showing the need for novel approaches to address such problems. In this regard, nanotechnology has a strong potential for both the diagnosis and therapy of UTIs via controlled delivery of antimicrobials upon stable, effective and sustained drug release. On one side, nanoscience allowed the production of various nanomaterial-based evaluation tools as precise, effective, and rapid procedures for the identification of UTIs. On the other side, nanotechnology brought tremendous breakthroughs for the treatment of UTIs based on the use of metallic nanoparticles (NPs) for instance, owing to the antimicrobial properties of metals, or of surface-tailored nanocarriers, allowing to overcome multidrug-resistance and prevent biofilm formation via targeted drug delivery to desired sites of action and preventing the development of cytotoxic processes in healthy cells. The goal of the current study is therefore to present the newest developments for the diagnosis and treatment of UTIs based on nanotechnology procedures in relation to the currently available techniques.

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“…Silver NPs target the respiratory system and cell division of microorganisms that eventually result in cell death ( Panáček et al, 2018 ). Copper nanoparticles have a similar antibacterial mechanism in urinary tract infection ( Al-Enizi et al, 2018 ). Titanium dioxide nanoparticles have also been used to destroy bacterial cells ( Zheng et al, 2018 ).…”

Section: Application Of Functionalized Nanomaterials In Prostatitismentioning

confidence: 99%

Therapeutic Applications of Functional Nanomaterials for Prostatitis

Liu

Chen

et al. 2021

Front. Pharmacol.

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Prostatitis is a common disease in adult males, with characteristics of a poor treatment response and easy recurrence, which seriously affects the patient’s quality of life. The prostate is located deep in the pelvic cavity, and thus a traditional infusion or other treatment methods are unable to easily act directly on the prostate, leading to poor therapeutic effects. Therefore, the development of new diagnostic and treatment strategies has become a research hotspot in the field of prostatitis treatment. In recent years, nanomaterials have been widely used in the diagnosis and treatment of various infectious diseases. Nanotechnology is a promising tool for 1) the accurate diagnosis of diseases; 2) improving the targeting of drug delivery systems; 3) intelligent, controlled drug release; and 4) multimode collaborative treatment, which is expected to be applied in the diagnosis and treatment of prostatitis. Nanotechnology is attracting attention in the diagnosis, prevention and treatment of prostatitis. However, as a new research area, systematic reviews on the application of nanomaterials in the diagnosis and treatment of prostatitis are still lacking. In this mini-review, we will highlight the treatment approaches for and challenges associated with prostatitis and describe the advantages of functional nanoparticles in improving treatment effectiveness and overcoming side effects.

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Cellulose gum and copper nanoparticles based hydrogel as antimicrobial agents against urinary tract infection (UTI) pathogens

Cited by 47 publications

References 47 publications

Nanoparticles as Potential Novel Therapies for Urinary Tract Infections

Nanoparticles as Potential Novel Therapies for Urinary Tract Infections

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections

Therapeutic Applications of Functional Nanomaterials for Prostatitis

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