Cellulitis, Necrotizing Fasciitis, and Subcutaneous Tissue Infections

Pasternack,

doi:10.1016/b978-0-443-06839-3.00090-4

Cited by 29 publications

(18 citation statements)

References 205 publications

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“…Oral penicillin V (phenoxymethylpenicillin) is a reasonable first choice, but optimal dosing of this agent is not well established. [5][6][7] Although monthly administration of 1.2 MU of intramuscular benzathine penicillin is recommended as an alternative to oral penicillin V, this dosing regimen was shown to be effective only in those patients not at risk of cellulitis recurrence. 28 Some experts recommend intramuscular administration of benzathine penicillin every 2 to 3 weeks for individuals who break through once-monthly intramuscular benzathine penicillin regimens.…”

Section: Recurrent Cellulitismentioning

confidence: 99%

Antimicrobial Prophylaxis in Adults

Enzler

Berbari

Osmon

2011

Mayo Clinic Proceedings

176

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Antimicrobial prophylaxis is commonly used by clinicians for the prevention of numerous infectious diseases, including herpes simplex infection, rheumatic fever, recurrent cellulitis, meningococcal disease, recurrent uncomplicated urinary tract infections in women, spontaneous bacterial peritonitis in patients with cirrhosis, influenza, infective endocarditis, pertussis, and acute necrotizing pancreatitis, as well as infections associated with open fractures, recent prosthetic joint placement, and bite wounds. Perioperative antimicrobial prophylaxis is recommended for various surgical procedures to prevent surgical site infections. Optimal antimicrobial agents for prophylaxis should be bactericidal, nontoxic, inexpensive, and active against the typical pathogens that can cause surgical site infection postoperatively. To maximize its effectiveness, intravenous perioperative prophylaxis should be administered within 30 to 60 minutes before the surgical incision. Antimicrobial prophylaxis should be of short duration to decrease toxicity and antimicrobial resistance and to reduce cost.

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Section: Recurrent Cellulitismentioning

confidence: 99%

Antimicrobial Prophylaxis in Adults

Enzler

Berbari

Osmon

2011

Mayo Clinic Proceedings

176

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“…Swelling and crepitus of the scrotum quickly increase, and dark purple areas develop and progress to extensive scrotal gangrene. If the abdominal wall becomes involved in an obese patient with diabetes, the process spread extremely rapidly [32].…”

Section: Clinical Presentationsmentioning

confidence: 99%

Necrotizing Fasciitis: Current Concepts, Pathogensand Management

Mustafa¹,

Firdaus²,

Elllzam³

et al. 2017

IOSR JDMS

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Abstract:Necrotizing fasciitis (NF) is a severe disease of sudden onset that spreads rapidly. The disease is more common in the adults Medical imaging is helpful to confirm diagnosis. Initial treatment includes a combination of intravenous antibiotics including piperacillin/tazobactam, vancomycin, and clindamycin or ampicillinsulbactam combined with metronidazole, clindamycin or carbapenems(imipenem).Aggressive surgical debridement is always necessary. Amputation of infected limb(s) may be necessary. Ancillary therapies, neither a substitute for surgical debridement nor proven efficacy have been described. Some studies recommend using intravenous immunoglobulin (IVIG).Nutritional support is imperative. High mortality rates if left untreated. High index of suspicion and knowledge is essential for early diagnosis and outcomes of NF.

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“…1 Pathogens most frequently implicated in commonly encountered primary BSIs are outlined in Table 1.…”

Section: Common Primary Infectionsmentioning

confidence: 99%