Cellulite: An Evidence-Based Review

Luebberding, Stefanie; Krueger, Nils; Sadick, Neil S.

doi:10.1007/s40257-015-0129-5

Cited by 72 publications

(91 citation statements)

References 103 publications

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“…Satisfaction for subcutaneous fat reduction with RF was approximately 71 - 97%, according to patients’ self-reported data (4). However, significant statistical outcomes about the effects of RF on skin laxity and cellulite treatment were low and limited (30, 37). …”

Section: Resultsmentioning

confidence: 99%

Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat

Alizadeh

Halabchi

Mazaheri

et al. 2016

Int J Endocrinol Metab

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ContextToday, different kinds of non-invasive body contouring modalities, including cryolipolysis, radiofrequency (RF), low-level laser therapy (LLLT), and high-intensity focused ultrasound (HIFU) are available for reducing the volume of subcutaneous adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or necrosis adipose tissue. In addition to the mentioned techniques, some investigations are underway for analyzing the efficacy of other techniques such as whole body vibration (WBV) and extracorporeal shockwave therapy (ESWT). In the present review the mechanisms, effects and side effects of the mentioned methods have been discussed. The effect of these devices on cellulite or subcutaneous fat reduction has been assessed.Evidence AcquisitionWe searched pubmed, google scholar and the cochrane databases for systemic reviews, review articles, meta-analysis and randomized clinical trials up to February 2015. The keywords were subcutaneous fat, cellulite, obesity, noninvasive body contouring, cryolipolysis, RF, LLLT, HIFU, ESWT and WBV with full names and abbreviations.ResultsWe included seven reviews and 66 original articles in the present narrative review. Most of them were applied on normal weight or overweight participants (body mass index < 30 kg/m2) in both genders with broad range of ages (18 to 50 years on average). In the original articles, the numbers of included methods were: 10 HIFU, 13 RF, 22 cryolipolysis, 11 LLLT, 5 ESWT and 4 WBV therapies. Six of the articles evaluated combination therapies and seven compared the effects of different devices.ConclusionsSome of the noninvasive body contouring devices in animal and human studies such as cryolipolysis, RF, LLLT and HIFU showed statistical significant effects on body contouring, removing unwanted fat and cellulite in some body areas. However, the clinical effects are mild to moderate, for example 2 - 4 cm circumference reduction as a sign of subcutaneous fat reduction during total treatment sessions. Overall, there is no definitive noninvasive treatment method for cellulite. Additionally, due to the methodological differences in the existing evidence, comparing the techniques is difficult.

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Section: Resultsmentioning

confidence: 99%

Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat

Alizadeh

Halabchi

Mazaheri

et al. 2016

Int J Endocrinol Metab

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“…However, the treatments in these studies lacked longterm efficacy and longevity [1] . In fact, no one treatment is completely successful [1] .…”

Section: Discussionmentioning

confidence: 99%

“…However, the treatments in these studies lacked longterm efficacy and longevity [1] . In fact, no one treatment is completely successful [1] . Noninvasive therapies, such as endermologie, phosphatidylcholine, mesotherapy, radiofrequency devices, extracorporeal shock wave therapy, and several topical therapies may show some improvement, but all these therapies need multiple sessions, have questionable longterm sustainability, and are not cost effective [1] .…”

Section: Discussionmentioning

confidence: 99%

“…In fact, no one treatment is completely successful [1] . Noninvasive therapies, such as endermologie, phosphatidylcholine, mesotherapy, radiofrequency devices, extracorporeal shock wave therapy, and several topical therapies may show some improvement, but all these therapies need multiple sessions, have questionable longterm sustainability, and are not cost effective [1] . Invasive therapies for cellulite have been shown to be more efficacious when compared to noninvasive therapy.…”

Section: Discussionmentioning

confidence: 99%

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Cellulite Treatment Using Endoscopic Scissors

Alharthi

Alsufyani

2016

Journal of Dermatological Research

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The aim of this paper is to report a new surgical technique for cellulite treatment, using autoclavable endoscopic scissors to release the fibrous band under tumescent anesthesia with the least number of access wounds targeting the entire affected area. Twelve female patients, all who suffered from stage III on the Numberger-Muller cellulite classification, underwent the procedure Satisfaction rate was measured by the Global Aesthetic Improvement Scale (GAIS). Ten patients scored 4 on the GAIS, and two patients scored 3. This technique had minimal side effects and was cost effective.

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“…Fonte: (Hexsel & Soirefmann, 2011 Também está relacionada ao aparecimento da LG, a genética, tabagismo, distribuição do tecido adiposo, sedentarismo, estresse, idade, ingestão excessiva de cafeína e bebidas alcoólicas. Embora ainda não existam dados epidemiológicos exatos, a maioria dos estudos afirma que a celulite está presente em mais de 90% das mulheres pós-púberes e, de acordo com alguns autores, dada a sua natureza ubíqua a celulite é mais apropriadamente uma característica sexual secundária do que propriamente uma doença (Bravo et al, 2013;Christensen, 2014;Almeida, Kilian & Moreira, 2015;Luebberding, Krueger & Sadick, 2015).…”

Section: Lipodistrofia Ginóide E Adiposidade Localizadaunclassified

Ativos Cosméticos Para O Tratamento Da Lipodistrofia Ginóide E Adiposidade Localizada

Torres¹,

Ferreira²

2017

Psicodebate

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RESUMOO tratamento tópico para a lipodistrofia, adiposidade localizada e a celulite é amplamente utilizado na estética, principalmente em associação a outros recursos terapêuticos estéticos, contribuindo na obtenção de resultados satisfatórios. Os ativos tópicos incluem agentes que aumentam o fluxo da microcirculação, que reduzem a lipogênese e promovem a lipólise, que restabelecem a estrutura normal da derme e do tecido subcutâneo, e agentes que eliminam os radicais livres ou impedem sua formação. O objetivo do estudo foi realizar uma pesquisa qualitativa e bibliográfica sobre a ação dos principais ativos utilizados no tratamento da adiposidade localizada e celulite. Para tanto, foi realizada uma busca na base de dados Pubmed sobre os ativos tópicos utilizados no tratamento da celulite e adiposidade localizada, no período de 2006 a 2016. Foram identificados alguns ativos lipolíticos como as metilxantinas, que atuam aumentando os níveis de AMPc, o retinol, que aumenta a espessura do colágeno dérmico e melhora o contorno das fibras elásticas, melhorando o aspecto da pele, e a L-carnitina, que auxilia na continuidade da lipólise. Como anticelulíticos foram encontrados o Ginkgo biloba e a Centella asiatica que atuam, basicamente, melhorando a circulação sanguínea. Apesar dos avanços na área da cosmetologia, não foram encontrados princípios ativos inovadores. As metilxantinas são predominantes no tratamento dessas duas condições. É inegável que o tratamento tópico satisfatório, em última análise, dependerá de observação e acompanhamento da condição. Palavras-chaves:Tecido Adiposo; Lipodistrofia; Cosméticos; Celulite. ABSTRACTThe topical treatment for localized adiposity and cellulite is widely used in aesthetics, mainly in association with other aesthetic therapeutic resources, contributing in obtaining satisfactory results. Topical compounds include microcirculation-enhancing agents that reduce lipogenesis and promote lipolysis, which restore the normal structure of the dermis and subcutaneous tissue and agents that eliminate free radicals or prevent their formation. The objective of the study was to conduct a qualitative and bibliographical research on the action of the main assets used in the treatment of localized adiposity and cellulite. For this purpose, a search was made in the Pubmed database on the active substances used in the treatment of cellulitis and 1 Endereço eletrônico de contato:

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Cellulite: An Evidence-Based Review

Abstract: This article provides a systematic evaluation of the scientific evidence of the efficacy of treatment for cellulite reduction. No clear evidence of good efficacy could be identified in any of the evaluated cellulite treatments.

Cited by 72 publications

References 103 publications

Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat

Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat

Cellulite Treatment Using Endoscopic Scissors

Ativos Cosméticos Para O Tratamento Da Lipodistrofia Ginóide E Adiposidade Localizada

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