Magali Soumillon, Anamaria Necsulea, Manuela Weier, David Brawand, Xiaolan Zhang, Hongcang Gu, Pauline Barthès, Maria Kokkinaki, Serge Nef, Andreas Gnirke, Martin Dym, Bernard de Massy, Tarjei S. Mikkelsen, Henrik Kaessmann et al.
Abstract:Understanding the extent of genomic transcription and its functional relevance is a central goal in genomics research. However, detailed genome-wide investigations of transcriptome complexity in major mammalian organs have been scarce. Here, using extensive RNA-seq data, we show that transcription of the genome is substantially more widespread in the testis than in other organs across representative mammals. Furthermore, we reveal that meiotic spermatocytes and especially postmeiotic round spermatids have rema…
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