Cellular Dynamics and Genomic Identity of Centromeres in the Cereal Blast Fungus

Abstract

0A series of well-synchronized events mediated by kinetochore-microtubule interactions ensure 2 1 faithful chromosome segregation in eukaryotes. Centromeres scaffold kinetochore assembly and 2 2 3 1 strain of M. oryzae. The centromeres in M. oryzae are regional and span 57 to 109 kb 3 2 transcriptionally poor regions. No centromere-specific DNA sequence motif or repetitive 3 3 elements could be identified in these regions suggesting an epigenetic specification of 3 4 centromere function in M. oryzae. Highly AT-rich and heavily methylated DNA sequences were 3 5