Cellular Biomarkers in Mytilus galloprovincialis L. (Mediterranean Mussels) from Izmir Bay (Turkey)

Katalay, Selma; Ayhan, Melike Merve; Güler, Cenap; Aldağ, Ceyda; Kilic, Tunay; Yavaşoğlu, Nefise Ülkü Karabay

doi:10.1007/s00128-022-03597-1

Cited by 4 publications

(2 citation statements)

References 41 publications

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“…Küçüksezgin et al (2006) reported that the heavy metal concentrations in various fish in İzmir Bay ranged between 4.5 and 520 µg/kg for Hg, 0.10 and 10 µg/kg for Cd, and 0.10 and 491 µg/kg for Pb µg/kg; in the same study, metal concentrations in the sediments were found to be as follows: Hg, 0.05-1.3; Cd, 0.005-0.82; Pb, 14-113, and Cr, 29-316 µg/g. Cellular biomarkers and heavy metal concentration were investigated in mussels (Mytilus galloprovincialis L.) collected from eight different regions of İzmir Bay, and as a result, different levels of heavy metal pollution in İzmir Bay are an environmental problem (Katalay et al, 2022). Especially the Total PAH concentration was reported as 885,5+-244,5 ng/g dw.…”

Section: Discussionmentioning

confidence: 99%

A mutagenicity investigation of sediment from İzmir Inner Bay using Ames genotoxicity assay

Egüz,

Boyacıoğlu

2023

EgeJFAS

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İzmir Bay is one of the most important ecosystems of Aegean Region. Impacts of environmental pollution in the aquatic environments, especially impacts of pollution with mutagenic and carcinogenic substances on human health is an important area of research. Thus, it is required to incorporate short-term biological research methods to the molecular chemical analysis methods. By means of Ames’s assay, it is possible to determine mutagenic potential of several chemicals, environmental pollutants, sediments, and waste waters. After the treatment facility was established in İzmir Bay in 2000, no mutagenicity studies were carried out in the sediment. Ames’s mutagenicity assay without S9 fraction using TA98 and TA100 strains of Salmonella typhimurium was done at four different concentrations (125 μg, 250 μg, 375 μg, and 500 μg) in the sediment samples from six stations on İzmir Inner Bay in order to detect presence of chemicals that may cause mutagenic effects. Based on the results of Ames’s assay, it was found that especially Turan Area (Station 3, on which shipyard is located) among 6 stations on İzmir Bay was under mutagenic and toxic effect and Bostanlı Area (Station 6) was under intense toxic effect. Turan Area was under the influence of environmental pollutants that may cause frameshift mutations. According to the present study, İzmir Inner Bay was contaminated by mutagenic and toxic substances.

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Section: Discussionmentioning

confidence: 99%

A mutagenicity investigation of sediment from İzmir Inner Bay using Ames genotoxicity assay

Egüz,

Boyacıoğlu

2023

EgeJFAS

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“…Green mussels with sizes of 6-7 cm from Indian water experienced disruption in the lumen, i.e., lumen dilation and atrophy with the formation of cellular desquamate (Vasanthi et al, 2021). The destruction of cells in the tubules indicated necrosis (Katalay et al, 2016).…”

Section: Tissue Alterationmentioning

confidence: 99%

Histological Alteration of Green Mussel Perna viridis Organs Exposed to Microplastics

Rahim

Yaqin

2022

Squalen Bull. Marine Fisheries Postharvest Biotech.

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Microplastic in the oceans might interfere with the health of marine organisms, including the green mussels (Perna viridis). This is due to microplastic accumulation in mussels organs, such as gills, hepatopancreas, and gonads. Therefore, tissue alteration is a good indicator for ecological risk analysis and other ecotoxicological study activities. Green mussels with shells 4.1 to 5.0 cm in length were collected from Mandalle waters, Pangkep Regency (Pangkajene Islands), Indonesia. Green mussels were exposed for seven days to microplastic with concentrations of 0.05 (A), 0.5 (B), and 5 (C) g/L. The results showed that the higher the concentration of microplastics exposed to the green mussel, the higher the accumulation of microplastics in the body of the mussel, within the tested concentrations. The increased concentration of microplastics increased the level of tissue alteration in the gills, hepatopancreas, and gonads, with the most sensitive organ being the hepatopancreas. Overall, the study confirmed that the histological assay of mussel organs could be used as a biomarker in ecotoxicological studies.

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Evaluation of Health Risks Attributed to Toxic Trace Elements and Selenium in Farmed Mediterranean Mussels from Türkiye and Bulgaria

Dogruyol,

Mol,

Ulusoy

et al. 2024

Biol Trace Elem Res

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Farmed mussels accumulate contaminants from their production environment rather than releasing them into water. This study reveals potential health risks associated with selenium, cadmium, mercury, and lead resulting from the consumption of mussels (Mytilus galloprovincialis) cultured along the coasts of Türkiye and Bulgaria. The concentrations of Se and toxic trace metals were measured by inductively coupled plasma mass spectrometry (ICP-MS). The detection limits (LOD) were 0.100, 0.015, 0.025, and 0.180 µg/kg for Se, Cd, Hg, and Pb, respectively. The mean Se concentrations were between 1.305 and 1.957 µg/g, and toxic metals were below the maximum limits. Due to Turkish and Bulgarian consumers’ limited mollusk consumption, mussels could only provide a maximum of 7.35% of the daily Se need. THQ and TTHQ of Se, Cd, and methyl-Hg were below 1, indicating that farmed mussels were safe for consumption. Percent PTWI values were calculated only for Cd and MeHg, as the PTWI value for Pb was discarded by the authorities and not determined for Se. Accordingly, weekly mussel consumption did not pose any risks. The margin of exposure approach was used to evaluate Pb intake. MOE-SBP and MOE-NE were significantly higher than 10, designating no significant health risks. Long-term consumption of mussels also does not pose a carcinogenic risk regarding the TR index calculated between 10−5 and 10−6 for Pb. Positive HBVSe (10.13–37.27) indicated that Se in mussels overcame Hg-related potential health concerns. Consequently, mussels grown in Türkiye and Bulgaria did not pose a risk for human consumption, based on current risk analysis methods.

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Cellular Biomarkers in Mytilus galloprovincialis L. (Mediterranean Mussels) from Izmir Bay (Turkey)

Cited by 4 publications

References 41 publications

A mutagenicity investigation of sediment from İzmir Inner Bay using Ames genotoxicity assay

A mutagenicity investigation of sediment from İzmir Inner Bay using Ames genotoxicity assay

Histological Alteration of Green Mussel Perna viridis Organs Exposed to Microplastics

Evaluation of Health Risks Attributed to Toxic Trace Elements and Selenium in Farmed Mediterranean Mussels from Türkiye and Bulgaria

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