2009
DOI: 10.4161/cc.8.24.10151
|View full text |Cite
|
Sign up to set email alerts
|

Cell type-specific regulation of a replication origin residing within an AT-rich/LINE-1-rich isochore

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
9
0

Year Published

2015
2015
2015
2015

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(10 citation statements)
references
References 13 publications
1
9
0
Order By: Relevance
“…RESULTS AND DISCUSSIONS Figure 1c shows that, as compared to the cells of line CH, DNA replication initiation in the HEK 293 cells occurred additionally at the point AT2, which was used previously as a control one [11,21]. At the same time, initiation near ori 1 decreased sharply in the HEK 293 cells (approximately by five times).…”
Section: Real Time Q Pcr Methods With the Use Of Sybrmentioning
confidence: 90%
See 4 more Smart Citations
“…RESULTS AND DISCUSSIONS Figure 1c shows that, as compared to the cells of line CH, DNA replication initiation in the HEK 293 cells occurred additionally at the point AT2, which was used previously as a control one [11,21]. At the same time, initiation near ori 1 decreased sharply in the HEK 293 cells (approximately by five times).…”
Section: Real Time Q Pcr Methods With the Use Of Sybrmentioning
confidence: 90%
“…At the same time, local changes of chromatin, taking place within the limits of one zone of DNA replication initiation (at a distance of some kbp), easily change the activity of ori sites [14]. These data, suggesting a hierarchy at both the levels of organization of chromatin and regulation of its activity, could explain the greater epigenetic plas ticity of some components (for example, oris [11,14]) rather than a complete, i.e., extended unit such as an RD. The higher but less plastic level of chromatin organization seems to have a biological function.…”
Section: Introductionmentioning
confidence: 90%
See 3 more Smart Citations