Abstract:Conflicts of interestThe authors disclose no potential conflict of interest.Significance Using a mouse model expressing a fluorescently version of TFIIH, we showed that TFIIH concentration is tightly controlled and that this concentration is proportional to the cellular transcriptional activity and proliferation capacity.
AbstractThe basal transcription/repair factor TFIIH is a ten sub--unit complex essential for RNA polymerase II (RNAP2) transcription initiation and DNA repair. In both these processes TFIIH a… Show more
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