Cell-to-cell interactions revealed by cryo-tomography of a DPANN co-culture system
Matthew D. Johnson,
Doulin C. Shepherd,
Hiroyuki D. Sakai
et al.
Abstract:DPANN is a widespread and diverse group of archaea characterized by their small size, reduced genome, limited metabolic pathways, and symbiotic existence. Known DPANN species are predominantly obligate ectosymbionts that depend on their host for proliferation. The structural and molecular details of host recognition, host-DPANN intercellular communication, and host adaptation in response to DPANN attachment remain unknown. Here, we use electron cryotomography (cryo-ET) to show that the Microcaldus variisymbiot… Show more
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