Abbreviations: (AGE) advanced glycation end product, (ANOVA) analysis of variance, (BSA) bovine serum albumin, (ELISA) enzyme-linked immunosorbent assay, (HUVEC) human umbilical vein endothelial cell, (ICAM-1) intracellular adhesion molecule-1, (MTT) 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide, (PBS) phosphate-buffered saline Keywords: advanced glycation end products, cardiovascular diseases, diabetes mellitus, endothelial cells, thrombogenicity