Cell surface associated mucins: Structure and effects on cell adhesion

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma

“…'Inside-out' expression (designated 'pattern E', Figure 1) for MUC1 was present in a small percentage of the tumours and has been previously described by two of the authors (C.P., J.L.P.). 34 This pattern is specific for invasive micropapillary carcinoma, a subtype of ductal breast carcinoma with a high potential to metastasize to axillary lymph nodes. 35 We found no such relationship, however, nor did we find an association between 'inside out' expression and outcome.…”

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in ‘pure’ ductal carcinoma in situ of the breast

“…The patterns of MUC1 expression that have been predefined in our previous studies in a set of invasive ductal carcinomas of the breast were applied to DCIS in the present study 28 …”

“…9 The patterns of MUC1 expression that have been predefined in our previous studies in a set of invasive ductal carcinomas of the breast were applied to DCIS in the present study. 28 Because most DCIS lesions displayed a high overall percentage of MUC1 expression, we did not evaluate further overall expression as a prognostic parameter. Entire membranous expression was related to Her2 ⁄ neu negativity (P ¼ 0.042).…”