Cell structure in the islands of calleja in carnivore brains

The distribution of m4 muscarinic acetylcholine receptors in the islands of Calleja and striatum of rats and cynomolgus monkeys

“…Indeed, there are many unique aspects of the islands of Calleja, ranging from the size and packing density of the neurons found within them, to the their close association with blood vessels Meyer et al, 1989Meyer et al, , 1994, to the way in which the granule cells of the islands respond to various drugs (MacGibbon et al, 1994;Vahid-Ansari and Robertson, 1996;Wirtshafter, 1998). Likewise, although there are certain similarities between the cells of the islands and those of the olfactory bulb (Berezhnaia et al, 1998;Hosoya, 1973), there are, as the current study demonstrates, important differences as well. It may be that progress in understanding the function of the islands of Calleja will come more from a consideration of their many unique attributes than from an attempt to find similarities between them and other nearby structures in the basal forebrain.…”

“…Clear, but modest, staining was present within the external plexiform layers of the main and accessory olfactory bulbs. The marked contrast between the intensity of this staining and that seen in the islands of Calleja provides little support for the concept that mitral cells in the olfactory bulb are analogous to the medium sized cells of the islands of Calleja (Berezhnaia et al, 1998;Hosoya, 1973). Relatively light staining was also seen throughout the dorsal striatum, and occasional "patches" of intensified staining were seen in both rats and monkeys.…”

“…We studied both rats and cynomolgus monkeys, in which the islands tend to have a somewhat different structure. We also extended our investigations to the olfactory bulb in order to investigate possible similarities between this structure and the islands of Calleja (Berezhnaia et al, 1998;Hosoya, 1973).…”

Nonlesions, Unusual Cell Types, and Postmortem Artifacts in the Central Nervous System of Domestic Animals

“…17). 9 Many of these immature cells can be immunolabeled with an antibody specific for doublecortin, a microtubule-associated protein expressed by neuronal precursor cells and immature neurons (Figs. 18,19).…”