Cell manipulation in ultrasonic standing wave fields

Abstract

ABSTRACT

Trapping, transportation and separation of small particles by an acoustic needle

“…This indicates that the needle vibrates at a flexural mode in the rz plane [26]. Based on the above analysis and experimental result, the vibration velocity of the needle, which is parallel to the r-axis, is approximately assumed as (1) in the section very close to the tip (z = 0). In Eq.…”

“…In the previous and present researches related to this area, the manipulation includes trapping [1][2][3][4][5][6][7][8][9], concentration [10,11], filtration [12,13], separation [14][15][16][17], transportation [18], rotation [19], disruption [20], deformation [21] and so on of small particles with a diameter from several microns to several millimeters. Acoustic manipulation of nano-particles is also under investigation although there have been fewer positive research results so far.…”

Focusing in a quadrupole acoustic channel

“…This was established that particles can be concentrated under the action of Stokes drag force and acoustic radiation force depending on their size and sound frequency (see Czyz, 1990;Dain, Fichman, Gutfinger, Pnueli, & Vainshtein, 1995;Danilov & Mironov, 2000;Duhin, 1960;Nigmatulin, 1990;Vainshtein, Fichman, Shuster, & Gutfinger, 1996;Whitworth & Coakley, 1992). The acoustic radiation force was also used to position and levitate particles (see Anderson, Cluff, Lemmon, & Putnam, 2005;Coakley, Bardsley, Grundy, Zamani, & Clarke, 1989;Danilov & Mironov, 1984;Doinikov, 1997aDoinikov, , 1997bFuchs, 1964;Gopinath & Mills, 1994;Hertz, 1995;Hinds, Mallove, & First, 1977;Kaduchak, Sinha, & Lizon, 2002;King, 1934;Nyborg, 1984). In those works the particle motion was studied in situations when undisturbed fluid was at rest.…”

Sound induced lobed pattern in aqueous suspension film of micro particles

“…Stationary sound waves are used in the generation of these patterns. The physical effect indicated by these patterns has been used to visualize the vibration mode pattern [1], and to separate and filter particles from suspension [3][4][5][6][7][8][9][10][11][12][13]. It also has potential applications in the bio sensing, bio-chip fabrication, high end material fabrication, etc.…”