Cell interactions with superhydrophilic and superhydrophobic surfaces

Oliveira, Sara M.; Alves, Natália M.; Mano, João F.

doi:10.1080/01694243.2012.697776

Cited by 132 publications

(95 citation statements)

References 159 publications

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“…(Roach, et al, 2006;Lord, et al, 2010;Raffaini and Ganazzoli, 2013;Song and Mano, 2013;Oliveira, et al, 2014b) Controlling these features can synergistically improve cell behavior.…”

Section: Topographical Cues -Micro Sub-micro Nanomentioning

confidence: 99%

“…(Oliveira, et al, 2014b) A classical example is the case of roughness-wettability. (Neto, et al, 2011;Oliveira, et al, 2011b;Oliveira, et al, 2014b) Introducing nano/micro-roughness in a substracte in the first instance may represent a higher surface area available for cell growth. Nevertheless, the altered roughness might also change the surface wettability into values that are not as favorable for cell adhesion/growth.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

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Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

Oliveira

Reis

Mano

2015

Biotechnology Advances

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The design of 3D constructs with adequate properties to instruct and guide cells both in vitro and in vivo is one of the major focuses of tissue engineering. Successful tissue regeneration depends on the favorable crosstalk between the supporting structure, the cells and the host tissue so that a balanced matrix production and degradation are achieved. Herein, the major occurring events and players in normal and regenerative tissue are overviewed. These have been inspiring the selection or synthesis of instructive cues to include into the 3D constructs. We further highlight the importance of a multiscale perception of the range of features that can be included on the biomimetic structures. Lastly, we focus on the current and developing tissue-engineering approaches for the preparation of such 3D constructs: top-down, bottom-up and integrative. Bottom-up and integrative approaches present a higher potential for the design of tissue engineering devices with multiscale features and higher biochemical control than top-down strategies, and are the main focus of this review.

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“…(Roach, et al, 2006;Lord, et al, 2010;Raffaini and Ganazzoli, 2013;Song and Mano, 2013;Oliveira, et al, 2014b) Controlling these features can synergistically improve cell behavior.…”

Section: Topographical Cues -Micro Sub-micro Nanomentioning

confidence: 99%

Section: Accepted Manuscriptmentioning

confidence: 99%

Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

Oliveira

Reis

Mano

2015

Biotechnology Advances

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“…Nanostructured functionalities on surfaces have also potential in the diagnosis of cancer diseases in early stage [19,20] and blocking cancer cells growth [15]. In general, the cell adhesion is influenced by a lot of factors but the surface properties, such as wettability, roughness, surface charge, chemical functionalities, stiffness and interactions of scaffold degradation products [21] play the dominant role. In the biological applications, the wettability of nanostructured surface is considered to be the most important attribute of the nanostructured surfaces influencing cell adhesion [7] and biological response on artificial materials [21].…”

Section: Introductionmentioning

confidence: 99%

“…In general, the cell adhesion is influenced by a lot of factors but the surface properties, such as wettability, roughness, surface charge, chemical functionalities, stiffness and interactions of scaffold degradation products [21] play the dominant role. In the biological applications, the wettability of nanostructured surface is considered to be the most important attribute of the nanostructured surfaces influencing cell adhesion [7] and biological response on artificial materials [21]. It has been shown that cells achieve maximum attachment onto surfaces with moderate wettability [3,7].…”

Section: Introductionmentioning

confidence: 99%

New nanostructured nickel–polymer nanohybrids with improved surface hydrophobicity and effect on the living cells adhesion

Macko

Oriňák

Oriňáková

et al. 2015

Applied Surface Science

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“…Indeed, the mere presence of an implant can critically influence the tissue healing process; for instance, the biocompatibility of a biomaterial depends on its surface properties, such as chemistry and chemical functionalities, topography and roughness, wettability, surface charge, elasticity/stiffness, etc. 2,3 Consequently, implants with different surface properties are expected to affect differently the tissue integration. Titanium and its alloys, the most used materials for hard tissue replacement, are classified as bioinert, due to the passivation layer of amorphous titanium dioxide (TiO 2 ), which is naturally formed on the surface.…”

Section: Introductionmentioning

confidence: 99%

Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO₂ coatings

et al. 2015

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Even though Ti-based implants are the most used materials for hard tissue replacement, they may present lack of osseointegration on the long term, due to their inertness. Hydrothermal treatment (HT) is a useful technique for the synthesis of firmly attached, highly crystalline coatings made of anatase titanium dioxide (TiO 2 ), providing favorable nanoroughness and higher exposed surface area, as well as greater hydrophilicity, compared to the native amorphous oxide on pristine titanium. The hydrophilicity drops even more by photofunctionalization of the nanostructured TiO 2 -anatase coatings under UV light. Human mesenchymal stem cells exhibited a good response to the combination of the positive surface characteristics, especially in respect to the UVB pre-irradiation. The results showed that the cells were not harmed in terms of viability; even more, they were encouraged to differentiate in osteoblasts and to become osteogenically active, as confirmed by the calcium ion uptake and the formation of well-mineralized, bone-like nodule structures. In addition, the enrichment of hydroxyl groups on the HT-surfaces by UVB photofunctionalization accelerated the cell differentiation process and greatly improved the osteogenesis in comparison with the nonirradiated samples. The optimal surface characteristics of the HT-anatase coatings as well as the high potentiality of the photo-induced hydrophilicity, which was reached during a relatively short pre-irradiation time (5 h) with UVB light, can be correlated with better osseointegration ability in vivo; among the samples, the superior biological behavior of the roughest and most hydrophilic HT coating makes it a good candidate for further studies and applications.

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Cell interactions with superhydrophilic and superhydrophobic surfaces

Cited by 132 publications

References 159 publications

Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

New nanostructured nickel–polymer nanohybrids with improved surface hydrophobicity and effect on the living cells adhesion

Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO₂ coatings

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Cell interactions with superhydrophilic and superhydrophobic surfaces

Cited by 132 publications

References 159 publications

Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends

New nanostructured nickel–polymer nanohybrids with improved surface hydrophobicity and effect on the living cells adhesion

Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO2 coatings

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Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO₂ coatings