Cell disruption of Nannochloropsis sp. improves in vitro bioaccessibility of carotenoids and ω3-LC-PUFA

Bernaerts, Tom; Verstreken, Heleen; Dejonghe, Céline; Gheysen, Lore; Foubert, Imogen; Grauwet, Tara; Loey, Ann Van

doi:10.1016/j.jff.2019.103770

Cited by 75 publications

(45 citation statements)

References 48 publications

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“…To the best of our knowledge, there is only one available publication on carotenoid bioaccessibility from microalgae ( Nannochloropsis sp.) that employed the same simulated digestion model (Bernaerts et al., 2020), with the omission of the oral phase.…”

Section: Resultsmentioning

confidence: 99%

In vitro bioaccessibility of macular xanthophylls from commercial microalgal powders of Arthrospira platensis and Chlorella pyrenoidosa

Tudor

Gherasim

Dulf

et al. 2021

Food Science & Nutrition

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The bioaccessibility of the major carotenoids present in two commercial microalgal supplements in powder form was investigated through a standardized in vitro digestion method. The dried biomass of Arthrospira platensis contained β‐carotene (36.8 mg/100 g) and zeaxanthin (20.8 mg/100 g) as the main carotenoids as well as a high content of saturated fatty acids (61% of total fatty acids), whereas that of Chlorella pyrenoidosa was rich in lutein (37.8 mg/100 g) and had a high level of unsaturated fatty acids (65% of total fatty acids). In the case of the latter, lutein bioaccessibility was not statistically enhanced after the replacement of porcine bile extract with bovine bile extract in the in vitro digestion protocol and after the addition of coconut oil (17.8% as against to 19.2% and 19.2% vs. 18.5%, respectively). In contrast, the use of bovine bile extract along with co‐digestion with coconut oil significantly enhanced the bioaccessibility of zeaxanthin from A. platensis, reaching the highest bioaccessibility of 42.8%.

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Section: Resultsmentioning

confidence: 99%

In vitro bioaccessibility of macular xanthophylls from commercial microalgal powders of Arthrospira platensis and Chlorella pyrenoidosa

Tudor

Gherasim

Dulf

et al. 2021

Food Science & Nutrition

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show abstract

“…Nutrients, such as protein and fatty acids, are present in microalgae, which are surrounded by a cell wall. It is hypothesized that microalgae cell wall, being mainly composed by indigestible polysaccharides, cannot be degraded by the digestive enzymes present in the mouth, stomach, and small intestine ( 19 ). This would limit the nutrient digestibility and bioaccessibility, which has not been thoroughly investigated for many important compounds found in microalgae.…”

Section: Introductionmentioning

confidence: 99%

Biochemical and Nutritional Evaluation of Chlorella and Auxenochlorella Biomasses Relevant for Food Application

et al. 2020

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Microalgae are a source of potentially healthy and sustainable nutrients. However, the bioaccessibility of these nutrients remains uncertain. In this study, we analyzed the biomass composition of five commercial Chlorella and Auxenochlorella strains, and Chlorella vulgaris heterotrophically cultivated in our laboratory. Protein accounted for 65 ± 3% (w w −1 ) dry matter (DM) in all biomasses, except for the lab-grown C. vulgaris that contained 20% (w w −1 ) DM protein. The fatty acids content was comparable and ranged between 7 and 10% (w w −1 ) DM. Most of the biomasses had a ω6-polyunsaturated fatty acids (PUFAs)/ω3-PUFAs ratio <4, as recommended by nutritional experts. A recently published harmonized protocol for in vitro digestion was used to evaluate fatty acids and protein bioaccessibilities. Protein bioaccessibility ranged between 60 and 74% for commercial Chlorella and Auxenochlorella biomasses and was 43% for the lab-grown C. vulgaris . Fatty acids bioaccessibility was <7% in commercial biomasses and 19% in the lab-grown C. vulgaris . Taken together, the results show that microalgae are promising sources of bioaccessible protein. The limited fatty acids bioaccessibility indicates the need for alternative upstream and downstream production strategies.

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“…One of them endorses the use of coconut oil to increase 6% of ZEA bioaccesibility in goji berries [ 204 ]. However, despite the increase in the solubility of ZEA in lipid emulsions, it is necessary to subject the walls of the matrix to microstructural modifications, especially with microalgae, since they can influence the digestibility and bioaccesibility of CA [ 161 ]. Nevertheless, microalgae are useful as a source of ZEA in food formulations due to its good bioaccesibility and storage in studies carried out with mice [ 205 ].…”

Section: Mechanism Of Action Of Xanthophyllsmentioning

confidence: 99%

Xanthophylls from the Sea: Algae as Source of Bioactive Carotenoids

et al. 2021

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Algae are considered pigment-producing organisms. The function of these compounds in algae is to carry out photosynthesis. They have a great variety of pigments, which can be classified into three large groups: chlorophylls, carotenoids, and phycobilins. Within the carotenoids are xanthophylls. Xanthophylls (fucoxanthin, astaxanthin, lutein, zeaxanthin, and β-cryptoxanthin) are a type of carotenoids with anti-tumor and anti-inflammatory activities, due to their chemical structure rich in double bonds that provides them with antioxidant properties. In this context, xanthophylls can protect other molecules from oxidative stress by turning off singlet oxygen damage through various mechanisms. Based on clinical studies, this review shows the available information concerning the bioactivity and biological effects of the main xanthophylls present in algae. In addition, the algae with the highest production rate of the different compounds of interest were studied. It was observed that fucoxanthin is obtained mainly from the brown seaweeds Laminaria japonica, Undaria pinnatifida, Hizikia fusiformis, Sargassum spp., and Fucus spp. The main sources of astaxanthin are the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp. Lutein and zeaxanthin are mainly found in algal species such as Scenedesmus spp., Chlorella spp., Rhodophyta spp., or Spirulina spp. However, the extraction and purification processes of xanthophylls from algae need to be standardized to facilitate their commercialization. Finally, we assessed factors that determine the bioavailability and bioaccesibility of these molecules. We also suggested techniques that increase xanthophyll’s bioavailability.

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Cell disruption of Nannochloropsis sp. improves in vitro bioaccessibility of carotenoids and ω3-LC-PUFA

Cited by 75 publications

References 48 publications

In vitro bioaccessibility of macular xanthophylls from commercial microalgal powders of Arthrospira platensis and Chlorella pyrenoidosa

In vitro bioaccessibility of macular xanthophylls from commercial microalgal powders of Arthrospira platensis and Chlorella pyrenoidosa

Biochemical and Nutritional Evaluation of Chlorella and Auxenochlorella Biomasses Relevant for Food Application

Xanthophylls from the Sea: Algae as Source of Bioactive Carotenoids

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