Cell death during preoviposition period in Boophilus microplus tick

Proteomic Analysis of Cattle Tick Rhipicephalus (Boophilus) microplus Saliva: A Comparison between Partially and Fully Engorged Females

“…Ticks concentrate the blood meal by secreting excess water and ions back into the host through salivary secretion [40]. After detachment from the host, a signal triggers tick salivary gland degeneration [41], [42]. R. microplus ticks attach to its host as unfed larvae, and then proceed to feed and molt through nymphal and immature adult stages in a period that stretches to 12 days.…”

Vaccination with cyclin-dependent kinase tick antigen confers protection against Ixodes infestation

“…Salivary glands from partially engorged females exhibited the highest CDKs expression levels, which may be linked to the regeneration that occurs in the salivary glands during the feeding process, as observed in insects (Kahl et al, 1990;Anhê et al, 2007). In fully engorged female, signals triggers tick salivary gland degeneration (Bowman and Sauer, 2004) with apoptosis process (Freitas et al, 2007;Scopinho Furquim et al, 2008) and alteration in protein saliva composition . The tick I. persulcatus remains attached to its mammalian hosts for 3-7 days, initially feeding for short periods that are followed by bursts of salivation and intermittent resting intervals (Konnai et al, 2008a,b).…”

Autophagy and its physiological relevance in arthropods: Current knowledge and perspectives

“…61 In contrast to autophagic PCD in insects, 13,62 however, recent studies propose that in ticks the degradation of salivary glands during/ after feeding may occur by apoptosis rather than by autophagy. [63][64][65][66][67][68] Autophagy and PCD in regulating oogenesis and ovarian tissue physiology of D. melanogaster. Studies during Drosophila development have demonstrated that autophagy plays a role in cell death during development.…”