Celiac Disease in Oman: A Tertiary Centre Experience

Al-Lawati, Taha; Al-Musawi, Hashim Sadiq

doi:10.5001/omj.2013.17

Cited by 7 publications

(11 citation statements)

References 15 publications

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“…Data on the proportion of RVGE was available from the following countries: Egypt [ 17 - 21 ], Iran [ 18 , 22 - 27 ], Iraq [ 18 , 28 ], Jordan [ 18 , 29 ], Kuwait [ 30 ], Libya [ 18 , 31 , 32 ], Morocco [ 18 , 33 ], Oman [ 18 , 34 , 35 ], Saudi Arabia [ 36 - 40 ], Syria [ 18 ], Tunisia [ 18 , 41 - 46 ], Turkey [ 14 , 15 , 47 - 50 ], and Yemen [ 18 ]. No studies were found from Algeria, Bahrain, Israel, Qatar, and the United Arab Emirates.…”

Section: Resultsmentioning

confidence: 99%

“…Among the countries with the lowest proportion of RVGE (16% to 23%) were Saudi Arabia [ 36 - 40 ], Tunisia [ 18 , 41 - 46 ], and Egypt [ 17 - 19 , 51 ]. Those with the highest proportion of RVGE included Syria (61%) [ 18 ], Oman (50%) [ 18 , 34 , 35 ], and Kuwait (44%) [ 30 ]. One study covered the WHO Eastern Mediterranean region as a whole, including many of the above countries (Egypt, Iran, Iraq, Jordan, Libya, Morocco, Oman, Syria, Tunisia, and Yemen) as well as Afghanistan and Sudan [ 18 ].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population

Khoury¹,

Ogilvie²,

Khoury

et al. 2011

BMC Infect Dis

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BackgroundRotavirus gastroenteritis (RVGE) is the most common cause of severe childhood diarrhea worldwide. Objectives were to estimate the burden of RVGE among children less than five years old in the Middle East (Bahrain, Iran, Iraq, Israel, Jordan, Kuwait, Oman, Qatar, Saudi Arabia, Syria, UAE, Yemen), North Africa (Algeria, Egypt, Libya, Morocco, Tunisia) and Turkey.MethodsA comprehensive literature search was conducted in major databases on the epidemiology and burden of rotavirus among children less than five years old between 1999 and 2009. Data from each country was extracted and compared.ResultsThe search identified 43 studies. RVGE was identified in 16-61% of all cases of acute gastroenteritis, with a peak in the winter. RVGE-related hospitalization rates ranged from 14% to 45%, compared to 14%-28% for non-RVGE. Annually, RVGE caused up to 112 fatalities per 100,000 in certain countries in the region. Hospitalization costs ranged from $1.8 to $4.6 million annually, depending on the country. The most recent literature available showed that G1P[8] was the most prevalent genotype combination in 8 countries (range 23%-56%). G2P[4] was most prevalent in 4 countries (26%-48%). G9P[8] and G4P[8] were also frequently detected.ConclusionsRVGE is a common disease associated with significant morbidity, mortality, and economic burden. Given the variety and diverse rotavirus types in the region, use of a vaccine with broad and consistent serotype coverage would be important to help decrease the burden of RVGE in the Middle East and North Africa.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population

Khoury¹,

Ogilvie²,

Khoury

et al. 2011

BMC Infect Dis

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“…Studies on the prevalence of CD in the general population are available only from seven Asian countries. Although population‐based studies are not available from many Asian countries, the presence of CD has been described in the form of case‐series from China, Iraq, Pakistan, Uzbekistan, Kuwait, Lebanon, Oman, Syria, Taiwan, Singapore, Japan, and United Arab Emirates . In addition, case reports of CD have been published from some other Asian countries such as Bangladesh, South Korea, and Yemen .…”

Section: Discussionmentioning

confidence: 99%

“…Although populationbased studies are not available from many Asian countries, the presence of CD has been described in the form of case-series from China, Iraq, Pakistan, Uzbekistan, Kuwait, Lebanon, Oman, Syria, Taiwan, Singapore, Japan, and United Arab Emirates. 24,25,27,[44][45][46][47][48][49][50][51] In addition, case reports of CD have been published from some other Asian countries such as Bangladesh, South Korea, and Yemen. [52][53][54] There still are no reports on CD from many Asian countries such as Azerbaijan, Kazakhstan, Turkminstan, Afganistan, Kyrgyzstan, Tajikistan, Cambodia, Myanmar, Vietnam, Mongolia, Nepal, and Bhutan.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of celiac disease in Asia: A systematic review and meta‐analysis

Singh

Arora

Singh

et al. 2016

J of Gastro and Hepatol

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“… 4 It has however been poorly reported from the Arabian Gulf with studies from Saudi Arabia and Oman. 5 , 6 CD was reported in Kuwait in 1987 when Khuffash et al described 20 affected children and estimated the prevalence as 1:3,000 births. 7 Another report showed that CD was responsible for 18.5% of protracted diarrhea in children in Kuwait.…”

Section: Introductionmentioning

confidence: 99%

Celiac disease in children: is it a problem in Kuwait?

Al-Qabandi¹,

Buhamrah²,

Al‐Abdulrazzaq³

et al. 2014

CEG

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BackgroundCeliac disease (CD) is a chronic inflammatory disease of the small intestine triggered by gluten ingestion. The objective of this study is to describe our experience with CD children in Kuwait.MethodsThe records of children with CD seen in the pediatric gastroenterology unit between February 1998 and December 2010 were retrospectively reviewed. Patients were referred because of symptoms or positive CD antibody screening of a high-risk group (type 1 diabetes and Down syndrome).ResultsForty-seven patients were diagnosed: 53% were symptomatic and 47% were identified by screening. The median age at diagnosis was 66 (range 7–189) months. All cases were biopsy-proven except one. The symptomatic patients were significantly younger than those identified following screening (P<0.004). In the whole group, 66% were females and 77% were Kuwaitis; 9% had a positive family history of CD. The estimated cumulative incidence was 6.9/105. The median duration of symptoms before diagnosis was 8.5 (range 2–54) months. Failure to thrive was the most common presenting complaint (72%) followed by diarrhea (64%) and abdominal distension (56%). Atypical manifestations were seen in 60% of patients. Underweight and short stature were confirmed in 19% and 17% of patients, respectively. Overweight and obesity were detected in 14% and 6%, respectively. CD serology was based on a combination of antiendomysial and antigliadin antibodies. The median follow up was 24 (range 12–144) months. All patients were commenced on a gluten free diet, but good compliance was only achieved in 78%.ConclusionThe low frequency of childhood CD in Kuwait could probably be attributed to either an underestimation of the atypical presentations or failure of proper screening. Also, adherence to a gluten free diet is a major problem in our population.

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Celiac Disease in Oman: A Tertiary Centre Experience

Cited by 7 publications

References 15 publications

Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population

Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population

Prevalence of celiac disease in Asia: A systematic review and meta‐analysis

Celiac disease in children: is it a problem in Kuwait?

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