2013
DOI: 10.2298/sarh1302122r
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Celiac disease

Abstract: Celiac disease is a multysystemic autoimmune disease induced by gluten in wheat, barley and rye. It is characterized by polygenic predisposition, high prevalence (1%), widely heterogeneous expression and frequent association with other autoimmune diseases, selective deficit of IgA and Down, Turner and Williams syndrome. The basis of the disease and the key finding in its diagnostics is symptomatic or asymptomatic inflammation of the small intestinal mucosa which resolves by gluten-free diet. Therefore, the bas… Show more

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Cited by 20 publications
(20 citation statements)
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“…Our study included more female participants, which is in line with the results of other surveys. Namely, the authors have noticed that female population is more likely to suffer from coeliac disease (1.3-2:1) [1,11]. In our cohort, nearly 45% of children with coeliac disease belong to the older age group.…”
Section: Discussionmentioning
confidence: 52%
See 1 more Smart Citation
“…Our study included more female participants, which is in line with the results of other surveys. Namely, the authors have noticed that female population is more likely to suffer from coeliac disease (1.3-2:1) [1,11]. In our cohort, nearly 45% of children with coeliac disease belong to the older age group.…”
Section: Discussionmentioning
confidence: 52%
“…Coeliac disease is a chronic inflammatory disease of multifactorial etiology, which results from a polygenic predisposition and gluten exposure [1]. The only scientifically proven beneficial treatment is strict lifelong adherence to a gluten-free diet [2].…”
Section: Introductionmentioning
confidence: 99%
“…There is a considerable heterogeneity in clinical presentation, from malabsorption with chronic diarrhoea, poor growth in children, abdominal distension and weight loss to non-specific signs and symptoms (1,2). The disease affects about 1% of the population and has a negative impact on various aspects of life, including physical and social functioning.…”
Section: Introductionmentioning
confidence: 99%
“…Celiac disease (also called gluten-sensitive enteropathy or dependent disorder of the small intestine) is a multisystemic disorder that occurs in genetically-predisposed individuals and is associated with other autoimmune diseases [1] . In its essence, celiac disease is considered as an autoimmune enteropathy owing to the complex immune-mediated reaction to specific gluten-peptides [2] found in wheat and other grain products such as rye, barley, which, in celiac patients, cause villous atrophy and malabsorption.…”
Section: Introductionmentioning
confidence: 99%