Ceftriaxone Intercalated Nanostructures Used to Improve Medical Treatment

Visual analogue scale (VAS) is a psychometric scale applied to measure subjective characteristics. The purpose of our study was to evaluate the efficiency of Ulipristal acetate (UPA) compared with Dienogest for endometriomas related pain using VAS. We performed a randomized study on women with symptomatic endometriomas. The study was realized between January 2016�December 2018. The patients were randomized in two groups: Group A- that received UPA in doses of 5 mg daily for 12�13 weeks and Group B that received 2 mg Dienogest for 12�13 weeks. Each group received de VAS (Visual Analogue Scale) questionnaire before and after treatment. 70 women wereincluded in the study with 35 patients for each group. The age the mean age was 30.20 years. For Numeric Rating Scale before treatment in the group with UPA the median value was 6 (CI= 5.26, 6.51) and for group B the median was 5 (CI= 5.13, 5.66). After treatment for group A the median value was 4 (CI= 3.58, 4.29) and for group B the median value 4 (CI= 4.23, 4.6). For FRS before treatment in the group with UPA median value was 6 (CI= 5.87, 6.58) and for the group B median was 6 (CI= 6.16, 6.57). After treatment for group A the median value was 4 (CI= 4.12, 4.73) and for group B the median value 5 (CI= 4.9, 5.06). The pain significantly improved for group A. (p[ 0.05) VAS represent a good method to evaluate the quality of pain for patients with endometriomas. The UPA and Dienogest treatment improve the VAS parameters with better results for UPA in the present study.

Section: Resultsmentioning

confidence: 99%

The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)

Sima¹,

Albu²,

Ionescu³

et al. 2019

“…This ever-changing and diversifying microbial flora, depending on the natural sequence of the transition from the infant to the elderly, may still be in a favorable balance if the patients adhere to the rules of hygiene, oral mucosa, teeth, periodontium and the tonsils are healthy or if the maintenance treatments are done in a timely and properly qualitative manner [33][34][35].…”

mentioning

confidence: 99%

“…The pathology of the oro-maxilo-facial territor y comprises a wide range of diseases with primary or secondary infectious etiology, the mouth being the natural cavity of the organism with the most varied or variable contamination flora, representing the so-called normal flora or fundamental flora [34,35].…”

mentioning

confidence: 99%

The Role of Chemical Agents in the Microbial Flora with Major Risk of Interventios in Maxilo-facial Surgery

Stelea¹,

Constantin²,

Budacu³

et al. 2019

The pathology of the oro-maxilo-facial territory comprises a vast chapter of diseases with primary or secondary infectious etiology, the mouth being the natural cavity of the organism with the most varied and variable flora of bacterial contamination. By the continuity solutions created by the mechanical act of mastication, decubitus of defective prosthetic works, local dento-periodontal infectious processes, but especially of dental or small-scale interventions, open gates and possibilities of penetration into the blood circulation of the microorganisms, which cause the transient bacteria. The study included 243 randomly selected patients, with the address of the Oral and Maxillofacial Surgery Clinic in the period 2016-2018. The inoculation of microorganisms in the oral cavity in circulating blood as a result of oral surgery or dental care procedures is much more common than in other areas of the body. Aggressive dental maneuvers that create solutions of continuity of oral mucosa, gingiva, periodontal surgery, periodontal surgery techniques can cause bacteria.

“…The oral cavity hosts a complex microbial ecosystem with different species and development particularities according to the anatomic structure (lips, teeth, tongue, jugal mucosa, palate, saliva, gingival cleft) and the artificial constructions they are located on (bridges, dental prostheses). Numerous bacterial species interact either in a synergetic manner, creating the proper environment or the necessary food for the survival of others, or antagonistic manner -some species are in competition with the others for food and survival [1][2][3]. .…”

mentioning

confidence: 99%

Chemical and Biological Factors in Infectious Diseases The oral microbial flora

Eşanu¹,

Debita²,

Dorobăț³

et al. 2019

The wide concept of health does not benefit of a single definition, but of multiple definitions and this plurality is related to the knowledge assimilated and the socio-economic dynamics. This is due to the fact that health is an ongoing process, its notion changing with the passage of time. Thus, at international level, health is nowadays defined considering multiple criteria. In the last decade, the analysis of relevant statistical data presents an unfavourable evolution for the three major components of population dynamics: natality, mortality and external migration, accompanied by the deterioration of the entire demographic construction and tendencies of heading towards an imminent demographic drift. Humans protect themselves against the microbial aggression by using their inborn barriers and mechanisms that are completed and modulated by acquired barriers and mechanisms. For a microorganism to reach the internal environment and generate an infectious process, it must get through and overcome these barriers. In order to overcome these barriers, the infectious agent must first adhere to the surface of epithelial cells and then pass through the epithelium. Local defence mechanisms help limit the infection and present the antigen to the regional lymphatic ganglions, contributing at the initiation of the immune response. On the other hand, the infectious agent present in the lymphatic system causes lymphangitis and satellite adenitis, which stand as a filter in the infections� way. The study included 127 patients with bacterial infections that were studied from 2014 to 2018. Infection can be caused by certain species of germs whose main feature is pathogenicity. Specific infections are caused by a foreign infectious agent that has accidentally reached the oral cavity causing oral lesions (appear in the secondary phase of the general infection). Specific infections are individualized, caused by a single microbe (monomicrobial) while the non-specific ones are associated (polymicrobial).