Cefaclor vs amoxicillin in the treatment of acute, recurrent, and chronic sinusitis

Huck, W; Reed, Barbara D.; Nielsen, Richard W.; Rj, Ferguson; Gray, Douglas; Lund, G; ZoBell, D H; Moster, M B

doi:10.1001/archfami.2.5.497

Cited by 46 publications

(14 citation statements)

References 9 publications

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“…Of the remaining 9 articles, 1 specifically mentioned that prior antibiotic therapy did not exclude enrollment [17], and 8 did not specifically mention this factor [9,12,14,16,[19][20][21]27]. The weighted rates for the articles that specifically excluded patients who had received prior antibiotic therapy were also calculated and found to not be significantly different from rates calculated including all articles.…”

Section: Resultsmentioning

confidence: 99%

Staphylococcus aureus Is a Major Pathogen in Acute Bacterial Rhinosinusitis: A Meta-Analysis

Payne¹,

Benninger²

2007

Clinical Infectious Diseases

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Background. Acute bacterial rhinosinusitis is a common health problem in the United States. Appropriate recommendations for the treatment of acute bacterial rhinosinusitis are based on the prevalence and expected antimicrobial susceptibilities of specific pathogens.Methods. A meta-analysis was performed on the English language literature from the period 1990-2006, including prospective studies of antibiotic therapy for acute bacterial rhinosinusitis for which sinus cultures were required in the form of either maxillary sinus taps or middle meatal cultures. Weighted mean culture rates for Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus were abstracted from the included articles and compared according to culture technique.Results. Culture rates (i.e., the percentage of patients with positive culture results) were 32.7% for S. pneumoniae, 31.6% for H. influenzae, 10.1% for S. aureus, and 8.8% for M. catarrhalis. No statistically significant difference was seen between the culture rates for S. aureus and M. catarrhalis. Analysis of the effect of culture technique on the culture rates revealed no statistically significant difference.Conclusions. The prevalence of S. aureus among sinus cultures warrants its reconsideration as a major pathogen in acute bacterial rhinosinusitis. As a result, increasing trends of drug-resistant strains may complicate antibiotic recommendations.

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Section: Resultsmentioning

confidence: 99%

Staphylococcus aureus Is a Major Pathogen in Acute Bacterial Rhinosinusitis: A Meta-Analysis

Payne¹,

Benninger²

2007

Clinical Infectious Diseases

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“…There were a total of four [736][737][738][739] double-blind randomized trials comparing 2 individual antibiotic regimens head to head without the inclusion of a placebo arm. Clinical resolution of RS was the main endpoint in each study, and there was no identifiable difference between treatment arms.…”

Section: Viie4 Crssnp Management: Antibioticsmentioning

confidence: 99%

“…Short-term (9 to 14 days) use of antibiotics improved clinical symptoms such as nasal discharge and nasal blockage, and there was no difference in the clinical efficacy of several kinds of antibiotics. [737][738][739] Although there has been no trial directly investigating preoperative antibiotics and intraoperative condition, patient-reported symptoms have been shown to be correlated with intraoperative bleeding and longer surgery time. 1155 Therefore, preoperative oral antibiotics may be beneficial in patients presenting with acute exacerbation of symptom and purulent discharge on endoscopic examination.…”

Section: Xc2 Crssnp: Preoperative Oral Antibioticsmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

554

888

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Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

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“…104, 105 If purulence is present on examination in a CRS patient, short-term culture directed therapy has been recommended. 106, 107, 108 In CRSwNP patients that experience an acute exacerbation or persistent symptoms of CRS, a short course of systemic corticosteroid therapy remains the standard of care with the best early and long-term improvement in polyp scores, 109 although doxycycline may have a role in the patients as well 110 Current clinical practice guidelines recommend consideration of long-term macrolide therapy such as clarithromycin 250–500mg daily, roxithromycin 150mg daily, or azithromycin 500mg weekly for 3 months in patients with CRSsNP only, as patients with nasal polyps did not benefit from long-term macrolide therapy when compared with placebo. 111, 112, 104 The routine use of antibiotics in CRS when acute infection is not present has been recently called into question, given the cost and potential harms of antibiotic use when the effectiveness of this therapy is not clear.…”

Section: A General Approach To Antibiotic Therapy For Refractory Crsmentioning

confidence: 99%

Bacterial Pathogens and the Microbiome

Vickery

Ramakrishnan

2017

Otolaryngologic Clinics of North America

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Cefaclor vs amoxicillin in the treatment of acute, recurrent, and chronic sinusitis

Cited by 46 publications

References 9 publications

Staphylococcus aureus Is a Major Pathogen in Acute Bacterial Rhinosinusitis: A Meta-Analysis

Staphylococcus aureus Is a Major Pathogen in Acute Bacterial Rhinosinusitis: A Meta-Analysis

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Bacterial Pathogens and the Microbiome

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