CeCl₃ · 7H₂O/SiO₂ as an Efficient and Recyclable Catalyst for the Synthesis of Dihydropyrano[3,2‐b]chromenediones

Abstract

Dihydropyrano[3,2-b]chromenedione derivatives were synthesized in moderate-to-high yields in one-pot three-component reaction from the corresponding aromatic aldehydes, kojic acid, and dimedone, in the presence of catalytic amount ofCeCl3⋅7H2O/SiO2as a nontoxic, reusable, inexpensive, and easily available reagent, under solvent-free conditions.

Three-component reactions of kojic acid: Efficient synthesis of Dihydropyrano[3,2-b]chromenediones and aminopyranopyrans catalyzed with Nano-Bi2O3-ZnO and Nano-ZnO

“…Three-component reaction of kojic acid, aldehyde and 1,3-dicarbonyl compounds or malononitrile is one of the most important methodology for the synthesis of these heterocyclic systems. A various catalysts and conditions were reported for this reaction, including InCl3, 10 CAN, 11 Al2O3, 12 Bi(OTf)3, 13 CeCl3•7H2O/SiO2, 14 FeCl3-SiO2, 15 Fe3O4@SiO2, 16 ultrasonic irradiation, 17 imidazole, 18 piperidine, 19 Et3N, 20 and NH4VO3. 21 Kojic acid and its derivatives have wide range of applications in cosmetic, 22 medicine, 23 food, 24 agriculture 25 and chemical industries.…”