Cecilin, a 1-benzyl-β-carboline from aniba santalodora

Four β-Carboline Alkaloids from Roemeria hybrida

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Turkish Roemeria hybrida has furnished the new l-benzyltetrahydro-P-carbolines (-)-roecarboline [1] and (+)-norroecarboline [2], together with the new simple ß-carbolines roeharmine [3] and (->-1,2,3,4-tetrahydroroeharmine [4],Although a large number of l-benzyltetrahydroisoquinoline alkaloids that are derived biogenetically from two tyrosine units are known, the corresponding 1-benzyltetrahydro^-carbolines or 1-benzyl-ß-carbolines are very rare. In fact, only one such alkaloid was known prior to the present study, namely the optically inactive ceciline found in Brazilian Aniba santalodora (Lauraceae) (1).

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“…Turkish Roemeria hybrida has furnished the new l-benzyltetrahydro-P-carbolines (-)-roecarboline [1] and (+)-norroecarboline [2], together with the new simple ß-carbolines roeharmine [3] and (->-1,2,3,4-tetrahydroroeharmine [4],…”

Canthin-6-one and β-Carboline Alkaloids fromAerva lanata

“…The similarly substituted fl-carbolines, to which aervolanin (6) belongs, are also fairly rare. There were only five similar compounds described: 6-hydroxyharmane, 6-methoxyharmane (21), 6-bromoharmane (22), cecilin (6-methoxy-1 -p-hydroxybenzyl-f3-carboline) (23), and 6-hydro-…”

Synthesis and antibiotic activity of some β-Carboline alkaloids

“…,19^8). Compound 3 was synthetized using the same procedure as for 9_ that is, by condensation of dí.-trypto phan with D-hydroxyphenylpyruvic acid (Aguiar et al, 1980). OxΊdat¡on/decarboxi 1 at ion with K^Cr^^^/CH COOH/H^O led to compound Compound 8 was obtained by acetilation of 7, Compounds 3» 7 and 8 are new products.…”