CdZnTe strip detector SPECT imaging with a slit collimator

Zeng, G.L.; Gagnon, Daniel

doi:10.1088/0031-9155/49/11/010

Cited by 24 publications

(14 citation statements)

References 39 publications

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“…A different type of detector material that has become popular in recent years as a candidate to replace the scintillation crystal in SPECT is cadmium zinc telluride (CZT) [23,24]. CZT is a semiconductor crystal, not a scintillation crystal.…”

Section: Instrumentation To Detect Single Photonsmentioning

confidence: 99%

“…11), rather than having to go through the intermediate steps of scintillation light creation, collection, and photoelectric conversion in a photodetector. The main advantages of this direct conversion of the incoming photon energy to an electronic signal are that (1) the energy resolution (∼5-6% FWHM at 140 keV) is typically much better than for scintillation detectors [23,24], and (2) high intrinsic spatial resolution may be achieved using fine "pixels" defined by the electrode pattern deposited on the detector faces, rather than requiring arrays of miniscule discrete crystals. Since semiconductor crystals cannot be formed to be as large as scintillation crystals such as NaI(Tl), a CZT-SPECT detector panel typically comprises many submodules tiled together.…”

Section: Instrumentation To Detect Single Photonsmentioning

confidence: 99%

See 1 more Smart Citation

Primer on molecular imaging technology

Levin

2005

Eur J Nucl Med Mol Imaging

109

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Abstract. A wide range of technologies is available for in vivo, ex vivo, and in vitro molecular and cellular imaging. This article focuses on three key in vivo imaging system instrumentation technologies used in the molecular imaging research described in this special issue of Eur J Nucl Med Mol Imaging: positron emission tomography, singlephoton emission computed tomography, and bioluminescence imaging. For each modality, the basics of how it works, important performance parameters, and the state-ofthe-art instrumentation are described. Comparisons and integration of multiple modalities are also discussed. The principles discussed in this article apply to both human and small animal imaging.

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Section: Instrumentation To Detect Single Photonsmentioning

confidence: 99%

Section: Instrumentation To Detect Single Photonsmentioning

confidence: 99%

Primer on molecular imaging technology

Levin

2005

Eur J Nucl Med Mol Imaging

109

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show abstract

“…As with slit-slat collimators, a skew-slit guarantees high spatial resolution in one of the directions and an extension of the FOV in the other, thus reducing artifacts. A single slit was also proposed, in combination with a linear detector (31), as an alternative to reach high spatial resolution if compared with single pinhole collimators. In this application, a set of cadmium zinc telluride elements is mounted in a linear format instead of a rectangular one and is allowed to spin around the optical axis while rotating around the target, scanning a larger detection area.…”

Section: Slit-based Collimatorsmentioning

confidence: 99%

Methodological approaches to planar and volumetric scintigraphic imaging of small volume targets with high spatial resolution and sensitivity

Mejía

Galvis-Alonso

Braga

et al. 2009

Braz J Med Biol Res

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“…The gamma ray detectors are mainly based on planar scintillator crystals or arrays of finger-like scintillator crystals, readout via PSPMTs [22][23][24] . Another approach uses semiconductor arrays with CdTe 25 or CdZnTe semiconductor detectors [26][27][28][29][30] for direct-detection of gamma rays, as with the pixel detector used here.…”

Section: Introductionmentioning

confidence: 99%

Multimodal system for in vivo tumor imaging in mice

Autiero¹,

Celentano²,

Cozzolino³

et al. 2006

SPIE Proceedings

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We devised a multimodal planar imaging system for in vivo mouse imaging, employing four modalities: optical imaging, green and red fluorescence reflectance imaging, radionuclide imaging and X-ray radiography. We are testing separately, and then in a combined way, each detection mode, via in vivo mouse imaging, with the final purpose of identifying small implanted tumor masses, of providing early tumor detection and following metastatic dissemination. We describe the multimodal system and summarize its main performance, as assessed in our research work in the various stages of the development, in fluorescence and radionuclide tests on healthy or tumor bearing mice. For gamma-ray detection we used a semiconductor pixel detector (Medipix1 or Medipix2) that works in single photon counting. Laser-induced fluorescence reflectance imaging was performed in vivo using a pulsed light source to excite the fluorescence emission of injected hematoporphyrin (HP) compound, a CCD camera, a low pass filter and a commercial image analysis system. The bimodal system was used for the acquisition of combined images of the tumor area (fluorescence: animal top view; radionuclide: bottom view). It was shown that the tumor area can be imaged in a few minutes, with a few millimeter resolution (1 mm pinhole diameter), radioactively ( 99m Tc radiotracer), and with the fluorescence system and that, in one case, only one of the two modalities is able to recognize the tumor. A phantom study for thyroid imaging with 125 I source embedded in a simulated tissue indicated a spatial resolution of 1.25 mm FWHM with a 1 mm pinhole.

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CdZnTe strip detector SPECT imaging with a slit collimator

Cited by 24 publications

References 39 publications

Primer on molecular imaging technology

Primer on molecular imaging technology

Methodological approaches to planar and volumetric scintigraphic imaging of small volume targets with high spatial resolution and sensitivity

Multimodal system for in vivo tumor imaging in mice

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