CdTe amplification nanoplatforms capped with thioglycolic acid for electrochemical aptasensing of ultra-traces of ATP

Shamsipur, Mojtaba; Farzin, Leila; Tabrizi, Mahmoud Amouzadeh; Shanehsaz, Maryam

doi:10.1016/j.msec.2016.08.038

Cited by 32 publications

(8 citation statements)

References 33 publications

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“…2(ac)]. [10][11][12] All three dimensions of these nanomaterials are within 100 nm, more specifically <50 nm in most cases. Metal NPs as the most common representation of 0D nanostructures have a special place in nanomedicine.…”

Section: Classification Of Nanomaterialsmentioning

confidence: 99%

“…New techniques to improve brain visualization and assess drug permeability across the blood-brain barrier (BBB) are critically needed. For this purpose, Frigell et al 135 developed the synthesis of glucose (the brain's principal nutrient) coated AuNPs (GNPs) carrying BBB-permeable neuropeptides (C 11 GNP, LipGNP, C 11 -EnkGNP, Lip-EnkGNP, C 11 GlycopepGNP, Lip-GlycopepGNP) and a NOTA derivative as the chelator of the positron emitter 68 Ga (PET reporter) for in vivo tracking biodistribution. Depending on the nature of the ligands attached to the gold surface, a different biodistribution profile was observed.…”

Section: D Nanocarriersmentioning

confidence: 99%

“…However, advances in organic synthetic chemistry and radiochemistry as well as improved automated techniques for radiosynthesis have encouraged investigators in developing 11 C tracers for use in PET imaging studies. For example, 11 C in the form of [ 11 C]methyl iodide was used as a methylation agent to react with carboxylic acid and amine functional groups of ligands bound to Fe 3 O 4 NPs. 171 The surface coating ligands present on superparamagnetic NPs were radiolabeled to achieve dualmodality PET/MR imaging capabilities.…”

Section: D Nanocarriersmentioning

confidence: 99%

“…There are many 0D nanostructures, such as nanoparticles (NPs), quantum dots (QDs), and nanoclusters (NCs) in different terms [Fig. (a–c)] . All three dimensions of these nanomaterials are within 100 nm, more specifically <50 nm in most cases.…”

Section: Strategic Applications Of Nanomaterials In Nuclear Medicinementioning

confidence: 99%

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An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

Farzin¹,

Sheibani²,

Moassesi³

et al. 2018

J Biomedical Materials Res

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Section: Classification Of Nanomaterialsmentioning

confidence: 99%

Section: D Nanocarriersmentioning

confidence: 99%

Section: D Nanocarriersmentioning

confidence: 99%

Section: Strategic Applications Of Nanomaterials In Nuclear Medicinementioning

confidence: 99%

See 2 more Smart Citations

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

Farzin¹,

Sheibani²,

Moassesi³

et al. 2018

J Biomedical Materials Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…Aptamers are DNA, RNA, and peptides that have a specific affinity for particular substances [1,2], such as small molecules [3,4], ions [5,6], proteins [7,8], cells [9,10], and organisms [11,12]. Aptamers have many advantages over antibodies, which otherwise have similar properties to aptamers.…”

Section: Introductionmentioning

confidence: 99%

Effect of Hydrophobic Groups on Adsorption of Amino Acids to Solid Surfaces in Water

Fukushima

Hirano

Sato

2022

Preprint

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We calculated the free energies of adsorption between a solid wall and various arginine derivatives in water using molecular dynamics simulations. We varied the hydrophobic group size of the amino acids in two ways and the hydrophilicity of the solid wall in five ways. The free energy of adsorption decreased by increasing the hydrophilicity of the solid wall, regardless of the size of the hydrophobic group. Amino acids with small hydrophobic groups adsorbed on the solid wall with the strongest hydrophilicity, but the free energy of the amino acids with large hydrophobic groups was relatively small. The free energy of adsorption in benzene solvent increased by increasing hydrophilicity of the solid wall, yet analogously to results in water solvent was independent of the size of the hydrophobic group. We attribute these differences in free energy to the effect of solvent molecules localized on the solid wall. Thus, these results may modulate peptide adsorption on a solid surface by the size of the peptide’s hydrophobic groups.

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Signalling probe displacement electrochemical aptasensor for malignant cell surface nucleolin as a breast cancer biomarker based on gold nanoparticle decorated hydroxyapatite nanorods and silver nanoparticle labels

Farzin¹,

Shamsipur

Samandari

et al. 2018

Microchim Acta

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Nucleolin is a multifunctional protein that is markedly overexpressed on the surface of most cancer cells. By taking advantage of the high affinity and specificity of the AS1411 aptamer for nucleolin, a signalling probe displacement electrochemical aptasensor was developed. The thiolated AS1411 aptamer was conjugated to hydroxyapatite nanorods (HApNRs) decorated with gold nanoparticles (AuNPs). To further increase the electrical conductivity of the interface, the ionic liquid 1-ethyl-3-methylimidazolium alanine with its high ion conductivity was placed on the electrode surface. Then, the aptamer was immobilized on the modified electrode and conjugated to signalling c-DNA tagged with AgNPs (c-DNA@AgNPs). In the presence of the MCF7 target cells, the signalling probe is displaced and released from the electrode surface. This leads to a decrease in the current that is proportional to the concentration of cancer cells in the range from 10 to 10 cells mL, with a detection limit as low as 8 ± 2 cells mL (n = 3) (based as 3σ/m, where σ is the standard deviation of the blank and m is the slope of the calibration plot). This method presents a promising tool for highly sensitive and selective detection of surface nucleolin on MCF7 cancer cells. Graphical abstract HApNR-AuNP-AS1411 aptamer nanocomposite as an electrochemical sensing interface was immobilized on the gold electrode surface and conjugated to signaling c-DNA tagged with AgNPs for determination of surface nucleolin on MCF7 cancer cells.

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CdTe amplification nanoplatforms capped with thioglycolic acid for electrochemical aptasensing of ultra-traces of ATP

Cited by 32 publications

References 33 publications

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

Effect of Hydrophobic Groups on Adsorption of Amino Acids to Solid Surfaces in Water

Signalling probe displacement electrochemical aptasensor for malignant cell surface nucleolin as a breast cancer biomarker based on gold nanoparticle decorated hydroxyapatite nanorods and silver nanoparticle labels

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