CDC42 rs2473317 polymorphism is associated with schizophrenia: A case-control study in the Armenian population

Stepanyan, Ani; Ghazaryan, Hovsep; Atshemyan, Sofi; Zakharyan, Roksana; Khoyetsyan, Aren

doi:10.1016/j.euroneuro.2018.11.623

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Institute Of Molecular Biology Of Armenian National1

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2019

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“…On the contrary, CDC42 gene rs2473277 genetic variant was associated with schizophrenia in a recent genome-wide association study [2]. Inconsistency of our data with the published results might be explained due to a long period of isolation of Armenian population since the Bronze Age and subsequently a unique profile of rare disease alleles [4]. From the other side the genetic structure of Armenian population is still largely unknown, which forces as to employ candidate polymorphism approach to study CDC42 , since its involvement in the genetic susceptibility to schizophrenia is well documented.…”

Section: Institute Of Molecular Biology Of Armenian Nationalsupporting

confidence: 56%