CD99 Expression and Prognostic Impact in Glioblastoma: A Single-Center Cohort Study
Andrea Rocca,
Fabiola Giudici,
Carmine Antonio Donofrio
et al.
Abstract:Glioblastoma is the most frequent and aggressive brain tumor in adults. This study aims to evaluate the expression and prognostic impact of CD99, a membrane glycoprotein involved in cellular migration and invasion. In a cohort of patients with glioblastoma treated with surgery, radiotherapy and temozolomide, we retrospectively analyzed tumor expression of CD99 by immunohistochemistry (IHC) and by quantitative real-time polymerase chain reaction (qRT-PCR) for both the wild type (CD99wt) and the truncated (CD99s… Show more
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