Abstract:Background
Loss of CD56 expression has been regarded as a diagnostic marker of papillary thyroid carcinoma (PTC). However, certain variants of PTC can aberrantly express CD56.
Methods
Using a digital-image analysis tool, we evaluated H-scores of CD56 immunostaining in 216 thyroid tumors.
Results
The H-score of the CD56 of all PTCs was lower than that of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) (p < 0.001). The H-scores of CD56 were lower in classic PTC, the inf… Show more
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