CD2-1, the C-Terminal Region of Flagellin, Modulates the Induction of Immune Responses in Rice

Katsuragi, Yuya; Takai, Ryota; Furukawa, Takehito; Hikita, Hiroyuki; Morimoto, Takumi; Katayama, Takara; Murakami, Takahiko; Che, Fang‐Sik

doi:10.1094/mpmi-11-14-0372-r

Cited by 42 publications

(24 citation statements)

References 46 publications

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“…An inventory of elicitor-active patterns and PRRs has been extended in plants ; Table 1). Flagellin has different elicitor-active epitopes than flg22 Takeuchi et al, 2003;Katsuragi et al, 2015). One such epitope undergoing strong selection against elicitor activity, termed flgII-28, was revealed by population genomics study on field Pst isolates in tomato (Cai et al, 2011).…”

Section: Recognition Of Bacterial Mampsmentioning

confidence: 99%

Pattern recognition receptors and signaling in plant–microbe interactions

2018

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SUMMARYPlants solely rely on innate immunity of each individual cell to deal with a diversity of microbes in the environment. Extracellular recognition of microbe-and host damage-associated molecular patterns leads to the first layer of inducible defenses, termed pattern-triggered immunity (PTI). In plants, pattern recognition receptors (PRRs) described to date are all membrane-associated receptor-like kinases or receptor-like proteins, reflecting the prevalence of apoplastic colonization of plant-infecting microbes. An increasing inventory of elicitor-active patterns and PRRs indicates that a large number of them are limited to a certain range of plant groups/species, pointing to dynamic and convergent evolution of pattern recognition specificities. In addition to common molecular principles of PRR signaling, recent studies have revealed substantial diversification between PRRs in their functions and regulatory mechanisms. This serves to confer robustness and plasticity to the whole PTI system in natural infections, wherein different PRRs are simultaneously engaged and faced with microbial assaults. We review the functional significance and molecular basis of PRRmediated pathogen recognition and disease resistance, and also an emerging role for PRRs in homeostatic association with beneficial or commensal microbes.

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Section: Recognition Of Bacterial Mampsmentioning

confidence: 99%

Pattern recognition receptors and signaling in plant–microbe interactions

2018

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“…An additional region of bacterial flagellin from A. avenae was recently reported to elicit plant defense responses in rice (73). The immunogenic epitope, termed CD2-1, is C terminal to the flg22 region, and the OsFLS2 ortholog does not mediate its recognition, suggesting a different flagellin-receptor system evolved in rice (73).…”

Section: Traditional Mamp Receptor Systems Are More Dynamic Than Genementioning

confidence: 99%

Understanding Plant Immunity as a Surveillance System to Detect Invasion

Cook

Mesarich

Thomma

2015

Annu. Rev. Phytopathol.

461

408

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Various conceptual models to describe the plant immune system have been presented. The most recent paradigm to gain wide acceptance in the field is often referred to as the zigzag model, which reconciles the previously formulated gene-for-gene hypothesis with the recognition of general elicitors in a single model. This review focuses on the limitations of the current paradigm of molecular plant-microbe interactions and how it too narrowly defines the plant immune system. As such, we discuss an alternative view of plant innate immunity as a system that evolves to detect invasion. This view accommodates the range from mutualistic to parasitic symbioses that plants form with diverse organisms, as well as the spectrum of ligands that the plant immune system perceives. Finally, how this view can contribute to the current practice of resistance breeding is discussed.

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“…In recent years, it has been reported that specific plants have evolved to perceive peptides within bacterial flagellin other than flg22 (Cai et al, 2011;Clarke et al, 2013;Katsuragi et al, 2015). Several plants from the Solanaceae family are able to perceive a distinct 28 amino acid peptide within flagellin from several Pseudomonas syringae strains, named flgII-28 (Cai et al, 2011;Clarke et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

The Ralstonia solanacearum csp22 peptide, but not flagellin‐derived peptides, is perceived by plants from the Solanaceae family

Wei

Cáceres-Moreno

Jiménez-Gόngora

et al. 2018

Plant Biotechnology Journal

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Summary Ralstonia solanacearum, the causal agent of bacterial wilt disease, is considered one of the most destructive bacterial pathogens due to its lethality, unusually wide host range, persistence and broad geographical distribution. In spite of the extensive research on plant immunity over the last years, the perception of molecular patterns from R. solanacearum that activate immunity in plants is still poorly understood, which hinders the development of strategies to generate resistance against bacterial wilt disease. The perception of a conserved peptide of bacterial flagellin, flg22, is regarded as paradigm of plant perception of invading bacteria; however, no elicitor activity has been detected for R. solanacearum flg22. Recent reports have shown that other epitopes from flagellin are able to elicit immune responses in specific species from the Solanaceae family, yet our results show that these plants do not perceive any epitope from R. solanacearum flagellin. Searching for elicitor peptides from R. solanacearum, we found several protein sequences similar to the consensus of the elicitor peptide csp22, reported to elicit immunity in specific Solanaceae plants. A R. solanacearum csp22 peptide (csp22Rsol) was indeed able to trigger immune responses in Nicotiana benthamiana and tomato, but not in Arabidopsis thaliana. Additionally, csp22Rsol treatment conferred increased resistance to R. solanacearum in tomato. Transgenic A. thaliana plants expressing the tomato csp22 receptor (SlCORE) gained the ability to respond to csp22Rsol and became more resistant to R. solanacearum infection. Our results shed light on the mechanisms for perception of R. solanacearum by plants, paving the way for improving current approaches to generate resistance against R. solanacearum.

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CD2-1, the C-Terminal Region of Flagellin, Modulates the Induction of Immune Responses in Rice

Cited by 42 publications

References 46 publications

Pattern recognition receptors and signaling in plant–microbe interactions

Pattern recognition receptors and signaling in plant–microbe interactions

Understanding Plant Immunity as a Surveillance System to Detect Invasion

The Ralstonia solanacearum csp22 peptide, but not flagellin‐derived peptides, is perceived by plants from the Solanaceae family

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