CD-MOFs: From preparation to drug delivery and therapeutic application

Si, Yanxue; Luo, Huize; Zhang, Pai; Zhang, Chunliang; Li, Juanjuan; Jiang, Peng; Yuan, Wenbing; Cha, Ruitao

doi:10.1016/j.carbpol.2023.121424

Cited by 12 publications

(3 citation statements)

References 167 publications

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“…This innovative approach addresses the limitations inherent in traditional skin cancer treatments by offering a more effective, patient-friendly therapeutic alternative. 19,20…”

Section: Introductionmentioning

confidence: 99%

Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Scattolin,

Tonon,

Botter

et al. 2024

J. Mater. Chem. B

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“…This innovative approach addresses the limitations inherent in traditional skin cancer treatments by offering a more effective, patient-friendly therapeutic alternative. 19,20…”

Section: Introductionmentioning

confidence: 99%

Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Scattolin,

Tonon,

Botter

et al. 2024

J. Mater. Chem. B

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“…In contrast, Bio-MOFs composed of biomolecules and metal ions have gained attention among various MOFs materials due to their low cost, low toxicity, good reproducibility, and adherence to the principles of green chemistry [43,44] . Inexpensive biomolecules, such as amino acids, proteins, peptides, and porphyrins, can serve as ligands for synthesizing Bio-MOFs [45,46] . However, the study of Bio-MOFs for light hydrocarbon separation remains relatively limited compared to their use in carbon dioxide capture [47,48] .…”

Section: Introductionmentioning

confidence: 99%

Biological metal–organic frameworks for natural gas purification and MTO product separation

Li,

Wang,

Wang

et al. 2024

Chem Synth

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The use of porous solid adsorbents is an effective and excellent approach for the separation and purification of methanol-to-olefins product and methane (CH4). In this particular study, a series of adenine (AD)-based biological metal–organic frameworks (Bio-MOFs) {Their general formula is Cu 2 (AD) 2 (X) 2 [X = formic acid, acetic acid (AA), and propionic acid]} were proposed, which exhibited remarkable efficiency in the purification of CH4 and the separation of C3H6 from methanol-to-olefins product, ultimately yielding purified C2H4. The experimental findings demonstrate that different terminal ligands induce alterations in the pore microenvironment, consequently leading to variations in adsorption capacities and stability. Specifically, Cu-AD-AA exhibits the highest adsorption capacity and selectivity among the three MOFs, as confirmed by static adsorption isotherm testing and theoretical evaluation using ideal adsorbed solution theory (IAST) simulation. At 298 K and 1 bar, Cu-AD-AA exhibits 786 and 10.9 selectivity for C3H8/CH4 and C3H6/C2H4, respectively, surpassing the majority of MOFs materials. Furthermore, breakthrough experiments conducted in ambient conditions reveal that Cu-AD-AA possesses commendable separation capabilities, enabling one-step purification of C2H4 at varying proportions (C2H4/C3H6 = 50:50, 50:20, and 90:10), along with satisfactory recycling performance. Importantly, the synthesis of Cu-AD-AA utilizes simple and easily obtainable raw materials, thereby offering advantages such as cost-effectiveness, low toxicity, and facile synthesis that enhance its potential for industrial applications.

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“…The term metal-organic frameworks (MOFs) was first proposed in 1995, when Yaghi and Li reported a "zeolite-like" crystal structure with large rectangular channels formed by the coordination of Cu 2 + , 4,4'-bipyridyl, and nitrate ions. [1] Compared with traditional materials, MOFs have the characteristics of highly ordered structure, high porosity, large specific surface area, etc., and are widely used in many fields such as gas storage, [2] catalysis, [3] drug delivery, [4,5] ion separation, [6] sensing [7] and so on. In the initial stage, MOFs are prepared by diffusion technology, which is time-consuming and has a low yield.…”

Section: Introductionmentioning

confidence: 99%

Synthesis Strategies, Preparation Methods, and Applications of Chiral Metal‐Organic Frameworks

Zhang,

Cheng,

Pei

et al. 2024

Chemistry A European J

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Chiral metal‐organic framework (CMOFs) is a kind of material with great application value in recent years. Formed by the coordination of metal ions or metal clusters with organic ligands. It is widely used in chemistry, biology, medicine and materials science because of its ordered and adjustable pores, multi‐dimensional network structure, large specific surface area and excellent adsorption properties. In this paper, the synthesis strategies and preparation methods of chiral metal‐organic frameworks are reviewed. In addition, the applications of chiral metal‐organic framework materials in enantiomer recognition and separation, circularly polarized luminescence and asymmetric catalysis are systematically summarized. Finally, the challenges and prospects of the development of chiral metal‐organic frame materials are analyzed in detail.

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CD-MOFs: From preparation to drug delivery and therapeutic application

Cited by 12 publications

References 167 publications

Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Biological metal–organic frameworks for natural gas purification and MTO product separation

Synthesis Strategies, Preparation Methods, and Applications of Chiral Metal‐Organic Frameworks

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