Cd(II) Pseudohalide Complexes with N, N′‐Bis(3‐ethoxysalicylidenimino) 1,3‐Diaminopropane: Crystal Structures, Hirshfeld Surface, Antibacterial and Anti‐Biofilm Properties

Abstract

3 OH].CH 3 OH] (3). Crystal structures of complexes 1-3 were determined by single-crystal X-ray diffraction studies. The single-crystal X-ray diffraction analysis confirmed that complex 1 is an one-dimensional polymeric chain in which Cd(II) ions are bridged by one thiocyanate group bonding in an end-to-end fashion. Complex 2 is a centrosymmetric octanuclear complex with double endon azide (m 1,1 -N 3 À ) as linker. On the other hand, 3 is a dinuclear complex with terminally bound Cl À ions. Analysis of the structure revealed that all the complexes possess a 4membered Cd 2 (m 2 -O) 2 core fastened by the combined coordination action of a doubly deprotonated ligand. Complexes 1-3 have been successfully characterized by elemental analyses, IR and UV-Vis spectroscopy. The luminescent properties of complexes 1-3 have been studied in DMSO solution. The antibacterial and antibiofilm potential for complexes 1-3 were investigated against Gram-positive and Gram-negative bacterial strains. Intermolecular interactions with respect to percentages of hydrogen bonding of cadmium complexes were quantified by Hirshfeld surface.[a] Prof.

Two zinc (II) coordination polymers based on aliphatic ether Schiff base: Synthesis, crystal structure, antioxidation and fluorescence

“…The zinc (II) is coordinated with an N 2 O 2 donor set from two N atoms [N(1A), N(2)] and two O atoms [O(2A), O(3)] provided by two different ligands. The coordination of the Zn atom is best described as a distorted tetrahedron geometry which can be determined using the τ 4 geometry index, τ 4 = [360‐(β + α)]/141 (where α and β are the largest angles around the metal's center) . The four‐coordinates τ 4 values range from 1 for a perfect tetrahedral geometry to 0 for perfect square planar geometry.…”

Hexnuclear Cadmium(II) Cluster Constructed from Tris(2-methylpyridyl)amine (TPA) and Azides

“…Moreover, 1D coordination polymers of Cd 6 chair-shape cluster [Cd 6 (2-Acpy) 4 (N 3 ) 12 ] n (H 2 O) 2n ·(CH 3 OH) n and their corresponding pentadecanuclear Cd 15 crown-like cluster [Cd 15 12 (N 3 ) 30 ] n ·(CH 3 OH) n were isolated with 2-acetylpyridine (2-Acpy) under slightly different stoichiometric conditions [2,3]. An interesting series of discrete cadmium-azide clusters with diverse nuclearity and poly-azide-connectors containing tri- [35,36], tetra- [37,38], penta- [35], hexa- [39], hepta- [40] and even octa-cadmium centers [41] were also reported. Herein, we report the synthesis, crystal structure and the luminescent emission of the novel hexanuclear cluster, [Cd 6 (TPA) 4 (µ 3 -1,1,3-N 3 ) 4 (µ 2 -1,1-N 3 ) 6 ](ClO 4 ) 2 ·2H 2 O (1), where TPA = tris(2-methypyridyl)amine.…”

In vitro biological and in silico molecular docking and ADME studies of a substituted triazine-coordinated cadmium(II) ion: efficient cytotoxicity, apoptosis, genotoxicity, and nuclease-like activity plus binding affinity towards apoptosis-related proteins

“…Therefore, for the biological activity of Cd (II), various complexes are investigated while for toxicity studies, the Cd ion itself is assessed (L'Azou et al 2014;Ahamed et al 2020). A wide variety of biological activities of Cd(II) complexes such as DNA binding ability (Manikandan et al 2013;Morgan et al 2017;Alalawy et al 2020), cytotoxicity (Guan et al 2014;Fang et al 2018;Tsave et al 2019), genotoxicity (Khandar et al 2019;Rukk et al 2019), antibacterial (Korkmaz et al 2014;Majumdar et al 2018;Aljahdali and El-Sherif 2020;Gitarić et al 2020;Zhang et al 2020), antifungal (Korkmaz et al 2014;Aljahdali and El-Sherif 2020;Gitarić et al 2020), and antioxidant (Aljahdali and El-Sherif 2020) properties has come to the current research focus. The results of the past decade research on cadmium complexes, as potential anticancer drugs, are indicative of their cytotoxicity and induction of cell death via apoptosis (Luo et al 2016;Zhang et al 2017;Abyar et al 2019;Khandar et al 2019).…”