Cd(II) complexation with 1,1-dithiolate and nitrogen donors: synthesis, luminescence, crystal structure, and antifungal activity study

Abstract

2015) Cd(II) complexation with 1,1-dithiolate and nitrogen donors: synthesis, luminescence, crystal structure, and antifungal activity studyA new luminescent complex of Cd(II) with 1,1-dicyanoethylene-2,2-dithiolate [i-MNT 2− = {S 2 C:C (CN) 2 } 2− ] has been synthesized and characterized on the basis of spectroscopy and single-crystal X-ray diffraction analysis. Single-crystal X-ray diffraction analysis reveals that the cadmium(II) complex is five coordinate in a 1-D polymer. Biological screening in vitro of the complex has been tested against five fungi Synchytrium endobioticum, Pyricularia oryzae, Helminthosporium oryzae, Candida albicans (ATCC10231), and Trichophyton mentagrophytes by the disk diffusion method. The antifungal activity of the complex of Cd(II) is significant compared to K 2 iMNT on S. endobioticum, P. oryzae, H. oryzae, and T. mentagrophytes and proved to be crucial for the growth-inhibitor effect.A new luminescent complex of Cd(II) with 1,1-dicyanoethylene-2,2-dithiolate [i-MNT 2− = {S 2 C : C (CN) 2 } 2− ] with 1,3-diaminopropane (tn) and 4-methyl pyridine (γ-picoline) as secondary ligands has *Corresponding author. Downloaded by [University of Nebraska, Lincoln] at 03:23 06 April 2015been synthesized and characterized on the basis of spectroscopy and single-crystal X-ray diffraction analysis. Single-crystal X-ray diffraction analysis reveals that cadmium(II) is five coordinate in a 1-D polymer. Biological screening effects in vitro of the synthesized complex has been tested against five fungi Synchytrium endobioticum, Pyricularia oryzae, Helminthosporium oryzae, Candida albicans (ATCC10231), and Trichophyton mentagrophytes by the disk diffusion method. A comparative study of inhibition zone values of K 2 i-MNT·H 2 O and {[Cd(tn)(iMNT)(4-MePy)]·4H 2 O} n (1) indicates that the complex exhibits antifungal activity, whereas K 2 i-MNT·H 2 O became silent on S. endobioticum, P. oryzae, H. oryzae, C. albicans (ATCC10231), and T. mentagrophytes.

Synthesis, characterization, DFT calculations and antimicrobial activity of pentagonal-bipyramidal Zn(II) and Cd(II) complexes with 2,6-diacetylpyridine-bis(trimethylammoniumacetohydrazone)

“…In most of the cases, the coordination of ligands to Zn(II) enhanced their antimicrobial activity [44,[47][48][49]. Reported results [43][44][45][46][47][48][49][50][51][52][53] and the present work showed that stability, solubility, charge, geometry and nuclearity of Cd(II) and Zn(II) complexes determine their antimicrobial activity. is the total number of parameters refined.…”

“…In comparison with previously studied isothiocyanato Ni(II), Co(II) and Mn(II) complexes with 2,6-diacetylpyridinebis(trimethylammoniumacetohydrazone) [14], the Zn(II) and Cd(II) complexes exhibited better antimicrobial activity. The literature contains many reports dealing with antimicrobial properties of Zn(II) and Cd(II) complexes [43][44][45][46][47]. Due to the extremely toxic nature of Cd(II), its complexes mainly showed higher antimicrobial activity than Zn(II) complexes with the same ligands [48][49][50][51][52][53].…”

Multifunctional Transition Metal Complexes: Design, Synthesis, Luminescent Features, Electrical Behaviour, Nanostructure Morphology and Bioactive Properties with 1,1-Dicyanoethylene-2,2-dithiolate and p-Phenylenediamine Ligands

“…In addition to structural chemistry, 1,1-dithiolate complexes also exhibits host-guest properties [20], catalytic properties [21], etc. The biological investigations of these mixed ligand 1,1-dithiolate complexes is reported in the literature recently, which includes antifungal activities [22][23][24][25], antibacterial, cytotoxic activities [26,27], etc.…”

Solvent influence on the crystal structures of new cadmium tri-tert-butoxysilanethiolate complexes with 1,4-bis(3-aminopropyl)piperazine: luminescence and antifungal activity

“…Despite the toxic properties of the metal itself, the compounds are still studied for the purpose of assessing their biological activity. However, this is not the only area in which the applicability of cadmium compounds is under investigation, they have also been assessed for their structural, photochemical and catalytic suitability (Wing-Wah Yam et al, 1999;Singh et al, 2015;Keypour et al, 2009;Po ´łrolniczak et al, 2018;Buta et al, 2021).…”