CCT in Different Epilepsies With Grand Mal and Focal Seizures in 309 Children: Relation to Clinical and Electroencephalographic Data

Lagenstein, I; Hj, Sternowsky; Rothe, Marti Jill; Kh, Bentele; Kühne, G E

doi:10.1055/s-2008-1071400

Cited by 13 publications

(9 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Abnormal findings on CT scan of brain provide an idea about the degree of cerebral involvement in different type of epilepsies. [11] However, CT scan of brain cannot provide information on intricate changes in the fine structure of the brain as in cases of children with cerebral palsy.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinico - diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures

Patel

Jain

Iyer

et al. 2013

Ann Indian Acad Neurol

View full text Add to dashboard Cite

Background:Therapeutic relevance of computed tomography (CT) in children with partial seizures is reported to be remarkably low (1-2%). However, in the developing countries where infections involving the nervous system are common, routine CT scan of brain may help in finding treatable causes of seizures.Objective:Aim of this study was to evaluate the significance of CT scan of brain in the management of children with partial seizures.Materials and Methods:Children with partial epilepsy, whose predominant seizure type was focal motor seizures, were included in the study. CT scan of brain was done in all children aged between 1 month and 12 years with partial seizures of unknown etiology prospectively. The clinical findings of these children were noted along with the CT findings.Results:Between August 2001 and July 2002, of the 200 children with seizure disorder 50 children who satisfied the inclusion criteria were included in the study. CT scan of brain was normal in 16 children (32%) and was abnormal in 34 children (68%). Twenty children (~60% of abnormal scan) had potentially correctable lesions: Tuberculoma (n = 13), neurocysticercosis (n = 3), and brain abscess (n = 4). Five children had changes representing static pathology that did not influence patient management. The clinical features correlated with CT findings in 78% children.Conclusion:Children with partial motor seizures have high probability of having abnormal findings on CT scan of brain, especially, neuro-infections which are potentially treatable. Therefore, CT scan brain should be carried out in all children with partial motor seizures especially, in developing countries.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Previous studies, which have reported abnormal findings on CT scan of brain in children with seizure disorder, mainly have children of mixed cohort with or without neurological signs, and children with known seizure etiologies. [89101112]…”

Section: Introductionmentioning

confidence: 99%

Clinico - diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures

Patel

Jain

Iyer

et al. 2013

Ann Indian Acad Neurol

View full text Add to dashboard Cite

show abstract

“…The incidence of diffuse atro phies was a little higher in these investigations ( 17 and 18 %) compared to 11 % in our study; however the signif icance of this CT finding has to be interpreted very care fully in children. Focal atrophies were found in 18% by Bauer et al [ 1980], 13 % by Lagenstein et al [1980] and in 14% in our study. In most of our cases a parenchymal lesion accompanied the focal atrophy.…”

Section: Discussionmentioning

confidence: 58%

“…The frequency of pathological CT findings in our study (39%) corresponds to the findings of Lagenstein et al [1980] and Bauer et al [1980], who found 39 respec tively 37% in children with partial seizures. A higher rate of pathological CT findings was registered in the investi gations of Blom et al [1984], whose patients were mainly adults, and of Blume et al [1982], who investigated patients below 21 years.…”

Section: Discussionmentioning

confidence: 91%

See 1 more Smart Citation

Computed Tomography in Partial Epilepsies in Childhood

1988

View full text Add to dashboard Cite

The CT investigations of 156 children with partial epilepsies are analyzed. Pathological findings appeared in 39%, particularly atrophic changes and porencephalic lesions. According to the seizure type their incidence was higher in children who had secondary generalized seizures (46 %) than in children with isolated partial seizures (30%) or complex partial seizures with or without secondary generalization (16%). Furthermore, pathological findings occurred more frequently in children with perinatal etiology (37%) than in familial (26%) or idiopathic cases (10%). A symptomatic epilepsy due to a cerebral tumor or a vascular lesion was found in 10%. There was a high correlation between neurodevelopmental disturbances and abnormal CT findings, however also 17 neurological normal children had pathological CT findings.

show abstract