CCLRU Standards for Success of Daily and Extended Wear Contact Lenses

Terry, Robert L.; Schnider, Cristina M.; Holden, Brien A.; Cornish, Ruth; Grant, Tim; Sweeney, Deborah F.; Hood, Donna La; Back, Arthur

doi:10.1097/00006324-199303000-00011

Cited by 254 publications

(136 citation statements)

References 0 publications

Supporting

Mentioning

128

Contrasting

Unclassified

Order By: Relevance

“…The CCLRU decimalised grading scale was used for grading (1=very slight, 2=slight, 3=moderate, 4=severe) [25]. The van Bijsterveld score was used to grade the rose bengal staining of the cornea and conjunctiva (0=no staining to 3=confluent staining) [26].…”

Section: Ocular Surface Healthmentioning

confidence: 99%

Oral omega-6 essential fatty acid treatment in contact lens associated dry eye

Kokke

Morris

Lawrenson

2008

Contact Lens and Anterior Eye

View full text Add to dashboard Cite

This is the unspecified version of the paper.This version of the publication may differ from the final published version. and also a significant improvement in overall lens comfort at 6 months (p<0.01). Permanent repository linkTear meniscus height was increased in the EPO group at 6 months relative to baseline (p<0.01), although all other objective signs were unchanged. Conclusion:This study provides evidence for a beneficial effect of particular orally administered omega-6 fatty acids in alleviating dry eye symptoms and improving overall lens comfort in patients suffering from contact lens associated dry eye.

show abstract

Section: Ocular Surface Healthmentioning

confidence: 99%

Oral omega-6 essential fatty acid treatment in contact lens associated dry eye

Kokke

Morris

Lawrenson

2008

Contact Lens and Anterior Eye

View full text Add to dashboard Cite

show abstract

“…21 Similar scales have been developed to grade conjunctival hyperaemia. [22][23][24][25][26] These bulbar redness scales have utilised verbal descriptions, photographs, or paintings that illustrate an increasing level of conjunctival hyperaemia, and they have been particularly used in clinical studies of contact lens wear and dry eye. 22,[27][28][29][30][31] The grading scale is typically divided into four or five grades.…”

Section: Introductionmentioning

confidence: 99%

How red is a white eye? Clinical grading of normal conjunctival hyperaemia

Murphy

Lau

Sim

et al. 2006

Eye

View full text Add to dashboard Cite

Purpose To quantify the level of normal bulbar conjunctival hyperaemia using the Cornea and Contact Lens Research Unit (CCLRU) grading scale, and to investigate inter-observer agreement. Methods Bulbar conjunctival hyperaemia was assessed by two trained observers, using the CCLRU grading scale (zero to four units) interpolated into 0.1 increments, on the right eye of 121 healthy, non-contact lens-wearing subjects (male ¼ 58, female ¼ 63, median age ¼ 28 years, range 16-77). The eye was observed using a slit-lamp bio-microscope ( Â 10 magnification) under diffuse, white illumination. The subject's position of gaze was directed to allow grading of four quadrants: superior, nasal, inferior, and temporal conjunctiva. Bulbar redness was defined as the average of those four grades of conjunctival hyperaemia. A further twenty subjects were recruited to assess interobserver agreement (male ¼ 8, female ¼ 12, median age ¼ 23 years). Results The average bulbar redness was 1.93 (70.32 SD) units. The nasal (2.370.4) and temporal (2.170.4) quadrants were significantly redder than the superior (1.670.4) and inferior (1.770.4) quadrants (Po0.0001). Males had redder eyes than females by 0.2 units. Inter-observer 95% limits of agreement for bulbar redness was 0.38 units. Conclusions The average bulbar redness of 1.9 units was higher than expected, reflecting the design of the grading scale. A bulbar redness of greater than 2.6 units may be considered abnormal, and a change in bulbar redness of Z0.4 units may be significant.

show abstract

“…In general, overnight contact lens wear modulates the presence of inflammatory mediators and neutrophil numbers. Alteration in the inflammatory cell number may severely reduce the ability of the ocular surface of the clearance of bacteria or debris during sleep [17,18]. Prolonged or overnight contact lens wear resulting in corneal stress may contribute to increased corneal susceptibility to infections and inflammation.…”

Section: Cytokinesmentioning

confidence: 99%