CBCT image quality QA: Establishing a quantitative program

Taneja, Sameer; Barbee, David; Rea, Anthony; Malin, Martha

doi:10.1002/acm2.13062

Cited by 12 publications

(10 citation statements)

References 22 publications

(35 reference statements)

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“…Chief among these is the fact that data were collected at a single institution, albeit across a number of treatment units. Despite increasing standardization in CBCT acquisition and reconstruction, institution‐ and machine‐specific differences in imager characteristics remain a challenge 32 …”

Section: Discussionmentioning

confidence: 99%

Assessing the reproducibility of CBCT‐derived radiomics features using a novel three‐dimensional printed phantom

2021

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Purpose Radiomics modeling is an exciting avenue for enhancing clinical decision making and personalized treatment. Radiation oncology patients often undergo routine imaging for position verification, particularly using LINAC‐mounted cone beam computed tomography (CBCT). The wealth of imaging data collected in modern radiation therapy presents an ideal use case for radiomics modeling. Despite this, texture feature (TF) calculation can be limited by concerns over feature stability and reproducibility; in theory, this issue is compounded by the relatively poor image quality of CBCT, as well as variation of acquisition and reconstruction parameters. Methods In this study, we developed and validated a novel three‐dimensional (3D) printed phantom for evaluating CBCT‐based TF reliability. The phantom has a cylindrical shape (22 cm diameter and 25.5 cm height) with five inner inserts designed to hold custom‐printed rods (1 cm diameter and 10–20 cm height) of various materials, infill shapes, and densities. TF reproducibility was evaluated across and within three LINACs from a single vendor using sets of three consecutive CBCT taken with the head, thorax, and pelvis clinical imaging protocols. PyRadiomics was used to extract a standard set of TFs from regions of interest centered on each rod. Two‐way mixed effects absolute agreement intra‐class correlation coefficient (ICC) was used to evaluate TF reproducibility, with features showing ICC values above 0.9 considered robust if their Bonferroni‐corrected p‐value was below 0.05. Results A total of 63, 87, and 83 features exhibited test–retest reliability for the head, thorax, and pelvis imaging protocols respectively. When assessing stability between discreet imaging sessions on the same LINAC, these numbers were reduced to 5, 63, and 70 features, respectively. The thorax and pelvis protocols maintained a rich candidate feature space in inter‐LINAC analysis with 61 and 65 features, respectively, exceeding the ICC criteria. Crucially, no features were deemed reproducible when compared between protocols. Conclusions We have developed a 3D phantom for consistent evaluation of TF stability and reproducibility. For LINACs from a single vendor, our study found a substantial number of features available for robust radiomics modeling from CBCT imaging. However, some features showed variations across LINACs. Studies involving CBCT‐based radiomics must preselect features prior to their use in clinical‐based models.

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Section: Discussionmentioning

confidence: 99%

Assessing the reproducibility of CBCT‐derived radiomics features using a novel three‐dimensional printed phantom

2021

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“…As one of the main means of tumor treatment, radiation therapy is required by 70% of tumor patients at different stages of tumor disease ( 19 ). After one hundred years of development, radiotherapy equipment has incorporated deep therapy equipment from a single function, such as cobalt 60 development, to the mainstream of linear accelerator and mass child, heavy ion accelerator, and other advanced equipment.…”

Section: Discussionmentioning

confidence: 99%

Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging

Huang¹,

He²,

Xiong³

et al. 2022

Transl Cancer Res TCR

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Background: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging.Methods: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi'an Jiaotong University between December 2020 and December 2021 were retrospectively selected as the research cohort. Participants underwent whole brain imaging guided by MD-CRT combined with volume assessment to assess the patient's recent treatment effect, statistically acceptable dose irradiation treatment, and the incidence of adverse reactions. All patients were followed up to evaluate the long-term efficacy.Results: Among the 150 patients, 24 cases were in complete remission, 72 cases were in partial remission, 36 cases were in a stable condition, 18 cases were in deterioration, and the treatment of 96 cases (64.00%) was deemed effective. All participants were followed up, the mean survival was (62.37±1.24) months, 96 cases (64.00%) survived, and 54 cases (36.00%) had died. The average dose was (62.09±3.94) Gy. In terms of adverse reactions: brain edema occurred in 57 patients, accounting for 38.00%. Conclusions:The MD-CRT and functional imaging techniques for patients with metastatic tumor have high therapeutic accuracy, are associated with improved local control rate, prolonged survival, and cause little damage to normal tissues, with significant therapeutic effect, and can be widely used in clinical practice.

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“…The Pro‐CT MK II phantom was divided into five regions for assessments at different image quality metrics. In this experiment, the uniform region was filled with distilled water, and the high‐contrast region containing eight material inserts was used to measure the cupping artifact and CNR 26,27 . For each region of the reconstructed image, 10 slices along the rotation axis were used to analyze the image quality metrics.…”

Section: Methodsmentioning

confidence: 99%

“…In this experiment, the uniform region was filled with distilled water, and the high-contrast region containing eight material inserts was used to measure the cupping artifact and CNR. 26,27 For each region of the reconstructed image, 10 slices along the rotation axis were used to analyze the image quality metrics. Figure 5 shows the reconstructed images in the two regions and the regions of interest (ROIs) denoted by the red dashed circles for the calculation of the image quality metrics.…”

Section: Measurement Of Image Qualitymentioning

confidence: 99%

Evaluation of a two‐dimensional Moire‐free antiscatter grid for cone‐beam computed tomography

Kim¹,

Kang²,

Hwang³

et al. 2023

Medical Physics

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Background: Scatter radiation is a traditional problem in cone-beam computed tomography (CBCT). Accordingly, numerous methods have been researched for scatter reduction in terms of software-or hardware-based solutions. The concept of a two-dimensional antiscatter grid (2D-ASG) has been shown to provide a solution to the scatter reduction in CBCT. However, the use of an ASG makes it challenging to use in clinical CBCT systems because it causes Moire artifacts of the image. Purpose: We have developed a Moire-free 2D-ASG that was designed to solve the Moire artifact and the scatter radiation problems. We provide the experimental results pertaining to the image quality measurements from the evaluation of the 2D-ASG compared with those obtained from a one-dimensional antiscatter grid (1D-ASG) and no antiscatter grid (No-ASG) to demonstrate the quantitative extent of the improvements. Methods: The 2D-ASG, fabricated based on a sawing process with a graphite body, was prepared to evaluate image quality improvements. Projection images for Pro-CT MK II phantom were acquired using the CBCT testbed of sample rotation type and reconstructed by Feldkamp-Davis-Kress (FDK) algorithm without any filters. We measured the contrast-to-noise ratio (CNR) and uniformity index for the cupping artifacts of the 2D-ASG, 1D-ASG, and No-ASG cases. Results: 2D-ASG considerably reduced the cupping artifacts owing to the scatter reduction compared with the 1D-ASG and No-ASG cases. The cupping artifacts were reduced by 85% in the 2D-ASG compared with No-ASG, while the cupping artifacts were reduced by 63% in 1D-ASG compared with No-ASG. The 2D-ASG also yielded a CNR improvement. The average CNR improvements for eight insert materials were 47% in the 2D-ASG compared with No-ASG, while the CNR was improved by 36% in the 1D-ASG compared with No-ASG. Conclusions: We demonstrated that the Moire-free 2D-ASG improved the image quality by removing scatter radiation in CBCT compared with 1D-ASG and No-ASG. We believe that the Moire-free 2D-ASG can become one of the effective ways to solve the scatter radiation problem in CBCT images because it provides usability and has the potential to have synergistic effects on other methods, such as bow-tie filter and scatter correction.

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CBCT image quality QA: Establishing a quantitative program

Cited by 12 publications

References 22 publications

Assessing the reproducibility of CBCT‐derived radiomics features using a novel three‐dimensional printed phantom

Assessing the reproducibility of CBCT‐derived radiomics features using a novel three‐dimensional printed phantom

Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging

Evaluation of a two‐dimensional Moire‐free antiscatter grid for cone‐beam computed tomography

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