Cavernous sinus syndrome secondary to invasive aspergilosis with carotid involvement in a HIV pacient

Inda, I. Saldaña; Saldaña, A. Sancho; Rubio, S. García; Mur, Daniel Sagarra

doi:10.1016/j.nrleng.2020.08.019

Cited by 1 publication

(3 citation statements)

References 14 publications

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“…Diabetes mellitus was the most common comorbidity (89%) in our study, which is consistent with the findings of previous studies [7,10,11]. This observation may be related to the immunocompromised state of patients with diabetes, especially those with poor disease control.…”

Section: Discussionsupporting

confidence: 92%

“…A review of small-scale studies showed that the majority of enrolled patients are elderly individuals, which is consistent with our study; however, there are still several case reports on young and pediatric patients (Table 4) [4,7,9,10].…”

Section: Discussionsupporting

confidence: 91%

“…The results are summarized in Table 4. 6) fever ( 5) ptosis ( 5) diplopia ( 4) photophobia ( 2 14) headache (13) ptosis ( 9) fever ( 9) chemosis ( 8) eyelid swelling (5) trigeminal hypesthesia ( 5) hemiparesis (5) eye pain ( 4) exophthalmos ( 4) decreased visual activity (3) Facial palsy (3) dysarthria ( 3) seizure (2) Horner's syndrome (1) DM ( 10) CRI ( 2) CHF ( 1) RA ( 1) COPD ( 1) NPC (1) liver cirrhosis (1) sphenoid ( 13) ethmoid ( 11) maxillary (10) frontal ( 3)…”

Section: Discussionmentioning

confidence: 99%

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Clinical Outcomes of Severe Rhinosinusitis Complicated with Cavernous Sinus Syndrome

Lin,

Liu,

Dai

et al. 2024

JCM

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Background: Various diseases involving the cavernous sinus can cause a condition called cavernous sinus syndrome (CSS), which is characterized by ophthalmoplegia or sensory deficits over the face resulting from the compression effect of internal structure. While tumor compression is the most reported cause of CSS, statistical data on CSS caused by infections are limited. Its risk factors, treatment methods, and clinical outcomes are not well-documented. Methods: In this retrospective study, we reviewed the data of patients admitted to a tertiary medical center from 2015 to 2022 with a diagnosis of acute and chronic sinusitis and at least one diagnostic code for CSS symptoms. We manually reviewed whether patients were involved in two or more of the following cranial nerves (CN): CN III, CN IV, CN V, or CN VI, or at least one of these nerves with a neuroimaging-confirmed lesion in the cavernous sinus. Results: Nine patients were diagnosed with rhinosinusitis-related CSS. The most common comorbidity was type 2 diabetes, and the most common clinical manifestations were diplopia and blurred vision. The sphenoid sinus was the most affected sinus. One patient expired due to a severe brain abscess infection without surgery. The remaining patients underwent functional endoscopic sinus surgery, and 50% of the pathology reports indicated fungal infections. Staphylococcus spp. was the most cultured bacteria, and Amoxycillin/Clavulanate was the most used antibiotic. Only four patients had total recovery during the follow-up one year later. Conclusions: CSS is a rare but serious complication of rhinosinusitis. Patients with diabetes and the elderly may be at a higher risk for this complication. Even after treatment, some patients may still have neurological symptoms.

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Section: Discussionsupporting

confidence: 92%