Causes of stillbirth and death among children younger than 5 years in eastern Hararghe, Ethiopia: a population-based post-mortem study

Madrid, Lola; Alemu, Addisu; Seale, Anna C; Oundo, Joe; Tesfaye, Tseyon; Marami, Dadi; Yigzaw, Hiwot; Ibrahim, Alexander; Degefa, Ketema; Dufera, Tadesse; Teklemariam, Zelalem; Gure, Tadesse; Leulseged, Haleluya; Wittmann, Stefanie; Abayneh, Mahlet; Fentaw, Surafel; Temesgen, Fikremelekot; Yeshi, Melisachew M; Dubale, Mehret; Girma, Zerihun; Ackley, Caroline; Damisse, Berhanu; Breines, Markus; Orlien, Stian M S; Blau, Dianna M; Breiman, Robert F; Abate, Ebba; Dessie, Yadeta; Assefa, Nega; Scott, J Anthony G; Deresa, Merga; Mengesha, Gezahegn; Samuel, Tigistu; Taye, Eyoel; Aliyi, Mohammed; Feyissa, Gurmu; Tilahun, Yenenesh; Wakwaya, Getahun; Tadesse, Simegn; Asnake, Kidish; Ayalew, Mariamcher; Kidane, Azeb; Azore, Emmanuel; Berhanu, Mussie; Berihun, Mulu; Deresa, Mersan; Assegid, Nardos; Voller, Shirine; Mekonnen, Mahlet; Alemaheyu, Andualem; Sarkodie-Mensah, Nana; Morrison, Beth; Jibendi, Boniface; Worku, Asnake; Mirkuzie, Alemenesh; Getnet, Fentabil

doi:10.1016/s2214-109x(23)00211-5

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…Karateristik lengkap responden penelitian dijabarkan pada tabel 1. ) diikuti dengan kelainan kongenital sebanyak 24 (21%) (Madrid et al, 2023).…”

Section: Hasil Dan Pembahasanunclassified

Profil Maternal pada Kasus Kematian Neonatus di Rumah Sakit Umum Daerah (RSUD) Ciawi

Ity Sulawati,

Dean Ascha Wijaya,

William Gilbert Satyanegara

2023

JRIK

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In 2013, 4.6 million babies died worldwide before their first birthday, with 50% dying on the first day and nearly 75% within the first week. Most stillbirths and premature newborn deaths are attributable to birth complications that are preventable. The maternal profile in neonatal mortality cases plays an important role in understanding the factors that contribute to this high mortality rate. This cross-sectional study aims to determine the maternal profile of neonatal death cases at Ciawi Hospital, which were selected according to the criteria by total sampling based on medical record data from January 1, 2020, to December 31, 2020. The variables utilized in this study include maternal factors such as gestational age, type of delivery, twin pregnancy, presentation of pregnancy, medical condition of the mother, and obstetric problems. The data is presented in a descriptive format. Among the 58 respondents, the average age was 30.26 years, with a higher prevalence of preterm births (55.2%). The most frequently encountered medical condition in the maternal profile of neonatal deaths at Ciawi General Hospital is chronic hypertension. Conversely, the most common obstetric problems are premature rupture of membranes and oligohydramnios. Efforts to address medical issues in mothers can contribute to the reduction of neonatal mortality cases.

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“…Karateristik lengkap responden penelitian dijabarkan pada tabel 1. ) diikuti dengan kelainan kongenital sebanyak 24 (21%) (Madrid et al, 2023).…”

Section: Hasil Dan Pembahasanunclassified

Profil Maternal pada Kasus Kematian Neonatus di Rumah Sakit Umum Daerah (RSUD) Ciawi

Ity Sulawati,

Dean Ascha Wijaya,

William Gilbert Satyanegara

2023

JRIK

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Reliable cause-of-death data for better child health practice in Ethiopia

Misganaw

Worku

2023

The Lancet Global Health

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Validation of malaria-attributed deaths using verbal autopsy studies: a systematic review

Carshon-Marsh,

Bondy,

Witek

et al. 2024

Malar J

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Background Malaria contributes substantially to the persistent burden of child deaths in sub-Saharan Africa. Accurate and comprehensive malaria mortality data are crucial to monitor the progress in reducing malaria incidence and mortality. Verbal Autopsy (VA) ascertains the cause of death despite its limitations leading to misclassification errors. Minimally Invasive Tissue Sampling (MITS) is being conducted in some settings as an alternative to Complete Diagnostic Autopsy (CDA). The present study examines the validity of malaria-related deaths comparing VA diagnoses with those obtained through MITS and/or CDA. Methods A comprehensive literature search for original studies in English language using Ovid MEDLINE, Ovid Embase, CINAHL via EBSCO, Scopus, The Cochrane Library via Wiley, Google Scholar and searching the MITS Surveillance Alliance papers was carried out. The reference period was January 1, 1990–March 31, 2024. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were adopted. Results Among 71 articles identified in the databases, 21 matched the eligibility criteria. Qualitative syntheses showed that malaria Cause Specific Mortality Fractions (CSMFs) across various studies ranged from 2 to 31%. Plasmodium falciparum was mostly responsible for these deaths and the most common complications were anaemia and cerebral malaria. The sensitivity and specificity of the VA validation studies ranged from 18.4% to 33% and from 86.6% to 97%, respectively, and there was a high level of misclassification for both InSilico and Expert Algorithm VA for malaria compared to MITS. The overall concordance rates between MITS and CDA diagnoses ranged from 68 to 90%, with the highest concordance seen in deaths due to infectious diseases and malignant tumours. Clinical data increased diagnostic coincidence between MITS blind to clinical data and the gold standard CDA by 11%. Conclusions The comprehensive review finds that MITS demonstrated better accuracy compared to VA in diagnosing malaria-attributed deaths, particularly in hospital settings. The high specificity of malaria in VA diagnosis suggests population-based estimates of the proportion of deaths due to malaria are broadly plausible.

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Causes of stillbirth and death among children younger than 5 years in eastern Hararghe, Ethiopia: a population-based post-mortem study

Cited by 3 publications

References 22 publications

Profil Maternal pada Kasus Kematian Neonatus di Rumah Sakit Umum Daerah (RSUD) Ciawi

Profil Maternal pada Kasus Kematian Neonatus di Rumah Sakit Umum Daerah (RSUD) Ciawi

Reliable cause-of-death data for better child health practice in Ethiopia

Validation of malaria-attributed deaths using verbal autopsy studies: a systematic review

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