2018
DOI: 10.1080/10245332.2018.1446703
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Causes of microcytic anaemia and evaluation of conventional laboratory parameters in the differentiation of erythrocytic microcytosis in blood donors candidates

Abstract: This study showed that the values of haematological parameters, especially haematocrit, Hb, MCV, MCH, MCHC and red blood cell distribution width (RDW), are lower in patients with IDA, especially when associated with α-thal and therefore it may be useful to discriminate between the different types of microcytic anaemia.

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Cited by 7 publications
(3 citation statements)
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“…Majority of the children had microcytic anaemia (59.3%) that occurred abundantly in males (64.6%), those undernourished (64.3%) especially the stunted (66.2%) and those whose parents had primary level of education (63.0%). Microcytic anaemia result from defective synthesis of haemoglobin causing a reduction in its mean corpuscular volume and the most common causes include iron deficiency anaemia, anaemia of chronic disease, α- thalassemias and sideroblastic anaemia [ 34 36 ]. The high proportion of microcytic anaemia which is probably linked to the occurrence of microcytosis (70.9%) suggests iron deficiency is the main cause of anaemia in the population.…”
Section: Discussionmentioning
confidence: 99%
“…Majority of the children had microcytic anaemia (59.3%) that occurred abundantly in males (64.6%), those undernourished (64.3%) especially the stunted (66.2%) and those whose parents had primary level of education (63.0%). Microcytic anaemia result from defective synthesis of haemoglobin causing a reduction in its mean corpuscular volume and the most common causes include iron deficiency anaemia, anaemia of chronic disease, α- thalassemias and sideroblastic anaemia [ 34 36 ]. The high proportion of microcytic anaemia which is probably linked to the occurrence of microcytosis (70.9%) suggests iron deficiency is the main cause of anaemia in the population.…”
Section: Discussionmentioning
confidence: 99%
“…Majority of the children had microcytic anaemia (59.3%) that occurred abundantly in males (64.6%), those undernourished (64.3%) especially the stunted (66.2%) and those whose parents had primary level of education (63.0%). Microcytic anaemia result from defective synthesis of haemoglobin causing a reduction in its MCV and the most common causes include iron deficiency anaemia, anaemia of chronic disease, α-thalassemias and sideroblastic anaemia [34,35,36]. The high proportion of microcytic anaemia which is probably linked to the occurrence of microcytosis (70.9%) suggests iron deficiency is the main cause of anaemia in the population.…”
Section: Discussionmentioning
confidence: 99%
“…22,23 Esta pérdida pocas veces se recupera puesto que para mitigar lo que supone una sola sesión de donación los enterocitos encargados de la absorción del hierro en la dieta, tendrían que absorberlo todo y aun así tardarían entre15 y 20 días para restituir los niveles normales, lo que puede conllevar a una anemia por deficiencia de hierro en los donadores frecuentes. 3,24 Se sabe que los niveles de hemoglobina y hematocrito no sirven para la detección de depleción de hierro en pacientes con hemoglobina en niveles relativamente normales, lo que sugiere que estos casos pueden tener una deficiencia de hierro subclínica. 25,26 Además se ha observado en algunos estudios que 42% de los pacientes presentan bajos niveles de ferritina, cifra que aumenta con la frecuencia de las donaciones.…”
Section: Deficiencia De Hierrounclassified