Causes of Hypertensive Anterior Uveitis in Thailand

Khieu, Chansathya; Kongyai, Natedao; Pathanapitoon, Kessara; Eijk, Annemiek A. van der; Rothová, Aniki

doi:10.1080/09273948.2019.1678651

Cited by 12 publications

(6 citation statements)

References 22 publications

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“…Approximately 30.0% (9/30) of ocular hypertension demonstrated positive in PCR test and all were CMV. A Thailand study de ned ocular hypertension as IOP > 25mmHg and demonstrated 32% positivity in herpesviridae PCR, including 19% for CMV, 10% for HSV, and 3% for VZV [34]. In our study, 27 cases had IOP > 25mmHg and 25.9% (7/27) were positive for herpesviridae PCR with all CMV infections.…”

Section: Discussionsupporting

confidence: 50%

Epidemiology and Clinical Features of Anterior Uveitis: a Prospective Study

Chiang

Chen

Sheu

et al. 2022

Preprint

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Purpose: To report the pattern, epidemiology, and clinical features of anterior uveitis (AU) in southern TaiwanMethods: A prospective case series was performed to recruit patients with AU at two medical centers (Kaohsiung Chang Gung Memorial Hospital and Kaohsiung Veterans General Hospital) in southern Taiwan from December 1, 2018 to March 31, 2020. These patients enrolled were reviewed for clinical diagnoses, ocular presentations, and laboratory data, including aqueous polymerase chain reaction tests.Results: A total of 112 patients were included. The most common clinical diagnoses were idiopathic AU (37.5%), HLA-B27-associated acute AU (25.0%), and herpetic AU (18.8%); among herpetic etiology, cytomegalovirus (CMV) was the most common pathogen. Hypertensive AU was associated with older age, more males, and greater numbers of corneal edema, and fewer iris posterior synechiae. Compared with HLA-B27-associated acute AU, CMV AU was associated with older age, high intraocular pressure, more keratic precipitates, greater iris atrophy, more pseudophakia, and fewer pupil posterior synechiae. Conclusion: This prospective study identified the epidemiological and clinical features of AU in southern Taiwan. The most common etiologies were idiopathic AU, HLA-B27-associated acute AU, and herpetic (most CMV) AU.

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Section: Discussionsupporting

confidence: 50%

Epidemiology and Clinical Features of Anterior Uveitis: a Prospective Study

Chiang

Chen

Sheu

et al. 2022

Preprint

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show abstract

“…About 30.0% (9/30) of ocular hypertension cases had positive PCR test results, and all were CMVrelated. A study in Tailand defned ocular hypertension as IOP >25 mmHg and found 32% PCR positivity for Herpesviridae, including 19% for CMV, 10% for HSV, and 3% for VZV [38]. In our study, 27 cases had IOP >25 mmHg and 25.9% (7/27) were Herpesviridae PCR-positive, with all being CMV-related.…”

Section: Discussionsupporting

confidence: 46%

A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan

Chiang,

Chen,

Sheu

et al. 2023

Journal of Ophthalmology

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In this study, we reported the patterns, epidemiology, and clinical features of anterior uveitis (AU) in Taiwan, an area of Eastern Asia. This prospective, cross-sectional case series study was performed to identify patients with AU at two tertiary medical centers (Kaohsiung Chang Gung Memorial Hospital and Kaohsiung Veterans General Hospital) located at the southern Taiwan between December 1, 2018, and March 31, 2020. The clinical diagnoses, ocular presentations, and laboratory data, including the results of the aqueous polymerase chain reaction tests, were investigated in these patients. A total of 112 patients, with a mean age of 48.9 years, were included. Most patients (87.5%) presented with unilateral eye disease, with 30 cases of ocular hypertension at the first presentation (27%). The most common clinical diagnoses were idiopathic AU (37.5%), human leukocyte antigen (HLA)-B27-associated acute AU (25.0%), and herpetic AU (18.8%). Among patients with herpetic AU, cytomegalovirus (CMV) was the most common pathogen (17/21, 81%). Compared to HLA-B27-associated acute AU, CMV-related AU was mostly observed in patients that were older in age, exhibited higher intraocular pressure, more keratic precipitates, greater iris atrophy, and more pseudophakia, but was least reported in those with posterior synechiae. This prospective study identified the pattern and clinical features of AU in southern Taiwan.

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“…In elderly White females, posterior uveitis with retinal involvement was observed most frequently, while studies with a predominantly Black patient population primarily reported anterior uveitis 13,14 . Our patients had mean age of 42 years with male preponderance (66%) which was different from the study population in Korea which had mean age of 53 years and female preponderance 15 .…”

Section: Resultsmentioning

confidence: 98%

Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.

Ishaq,

Riaz,

Iqbal

et al. 2024

ashkmdc

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Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment.. Methods: We did an observational prospective study, after acquiring ethical review letter from IRB Medicine department outpatient services of Jinnah Medical College Hospital Korangi was used where patients with Uveitis were referred for evaluation of systemic disease during jan 2019 to dec 2020. These patients underwent history, examination and biochemical and radiological investigations and were followed over a period of 1 year to see response to treatment. Results: A total of 372 patients presented with established uveitis out of which 36 patients i.e. 66 eyes presented to our eye clinic with decrease in vision with a mean age of 42±2 years. Among 36 patients, 89% presented with redness of eye and 72% presented with eye pain where as 8 % pre- sented with photophobia and floaters. Biochemically >10mg/dl calcium was observed in 18(50%) pa- tients and ACE level was found to be more than 40nmol/ml/min in 30(83.3%) patients. Among them 32 (88.9%) patients showed resolved inflammation whereas 2(5.56%) showed a change in inflamma- tion and 2(5.56%) showed no change. Conclusion: We found sarcoid uveitis as fairly common cause of uveitis. The patients were treated with the standard treatment of steroids and immunosuppressants i.e. Azathioprine and we concluded that use of steroids and immunosuppressant improved the outcome in our patients. The patients re- sponded fairly well to the designed treatment.

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Causes of Hypertensive Anterior Uveitis in Thailand

Cited by 12 publications

References 22 publications

Epidemiology and Clinical Features of Anterior Uveitis: a Prospective Study

Epidemiology and Clinical Features of Anterior Uveitis: a Prospective Study

A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan

Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.

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