Causes of hospital admission in β‐thalassemia (CHAT) in Lebanon from 1995 to 2015: A pilot retrospective study from a tertiary care center

Saliba, Antoine N.; Moukhadder, Hassan M.; Harb, Afif; Beydoun, Hassan; Bou‐Fakhredin, Rayan; Taher, Ali T.

doi:10.1002/ajh.24900

Cited by 1 publication

(2 citation statements)

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“…Comparisons with studies from Iran, Sardinia, and Lebanon highlighted similarities in the major complications observed in hospitalized thalassemia patients, such as cardiac com-plications and diabetes mellitus [19][20][21]. However, differences were noted, including the absence of mesenteric lymphadenitis associated with desferrioxamine in the current study.…”

Section: Discussioncontrasting

confidence: 38%

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Causes of Hospitalizations in Pediatric Patients with Thalassemia under the National Health Coverage Scheme in Thailand

Charoenkwan,

Komvilaisak,

Thepsuthummarat

et al. 2024

Thalassemia Reports

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Thalassemia is a hereditary hemolytic anemia that is prevalent in Southeast Asia. The primary treatment for severe thalassemia involves red cell transfusion, iron chelation, and the treatment of long-term complications, leading to frequent hospital visits and admissions. This study aims to delineate the causes and characteristics of hospital admissions among thalassemia patients under the National Health Coverage (NHC) scheme in Thailand. This cross-sectional analysis (2015–2019), conducted using the National Health Security Office database, identified 336,054 admissions among 41,237 patients, with alpha-thalassemia at 12.5%, beta-thalassemia at 61.5%, other thalassemia at 0.5%, and unclassified thalassemia at 25.5%. The overall admission rate was 3.74 per 100 NHC admissions in the pediatric age group. Infections predominated in younger patients, whereas cardiac complications, diabetes mellitus, and cholecystitis/cholelithiasis were more common in older patients. Hospital admissions for cardiac complications and diabetes mellitus in pediatric patients with thalassemia decreased over the study period. The annual hospital admission cost ranged from 8.19 to 12.01 million US dollars, with one-third attributed to iron chelation. In summary, thalassemia poses a significant healthcare challenge in Thai children, characterized by high admission rates and costs. While infections predominate in younger patients, cardiac complications and diabetes mellitus are more common in older individuals. The diminishing admissions for these complications suggest the successful implementation of iron chelation medications.

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Section: Discussioncontrasting

confidence: 38%

“…The most common causes of admission were transfusion therapy, infections, and chemotherapy. Age was a single factor that was associated with a longer hospital stay [21].…”

Section: Discussionmentioning

confidence: 96%