Causes of death shortly after delivery and medical malpractice claims in congenital high airway obstruction syndrome: Review of the literature

Lupariello, Francesco; Nuzzolese, Emilio; Vella, Giancarlo Di

doi:10.1016/j.legalmed.2019.07.008

Cited by 8 publications

(9 citation statements)

References 34 publications

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“…This finding may be associated with higher mortality and permanent injury rates reported in cardiac, respiratory and plastic surgery congenital malformations. 8,14,15 However, compared to monetary damages in paediatric urology, BEEC payments were greater. 9,20 An estimated incidence of 75 new bladder exstrophy cases per year, 900 over the course of this study, allows us to comment on incidence of malpractice litigation in this sphere.…”

Section: Discussionmentioning

confidence: 99%

Bladder exstrophy-epispadias complex related litigation: A legal database review

et al. 2023

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Objective To review the nature and extent of bladder exstrophy-epispadias related malpractice litigation in the United States. Methods Two legal databases (Nexis Uni, WestLaw) were reviewed for state and federal cases using the terms “bladder exstrophy”, “cloacal exstrophy”, “epispadias”, in combination with “medical malpractice”, or “negligence”, or “medical error”, or “complication”, or “malpractice”, or “tort”. Databases were queried from 1948 to 2022 and reviewed for medical and legal details. Results Our search yielded 16 unique legal cases with 6 fitting established criteria for analysis. Urology and paediatric urologists were named in 50% of cases as were community medical systems. Cause for lawsuit included negligence in surgical performance (50%), primary closure of exstrophy (33%), and post-operative care (50%). Settlement agreement was reached in one case (17%). Outcomes favoured the physician in 60% of trials. Lawsuits alleging negligent surgical performance and/or post-operative care exclusively named urologists with outcomes favouring the surgeon in 66% of cases. The settlement payment (n = 1) was $500,000 and monetary damages (n = 1) equated to $1.3 million. Conclusions Malpractice litigation related to BEEC treatment is rare. Trial outcomes favour the medical provider. Cases that resulted in financial liability successfully alleged avoidable negligence resulting in irreversible physical damage. The authors recommend families with BEEC seek board-certified paediatric urologists experienced in treating this complex and/or Bladder Exstrophy Centers of Excellence. Further, we recommend surgeons treating BEEC properly educate patients and families on the severity of this major birth defect including its lifelong implications and need for surgical revisions.

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Section: Discussionmentioning

confidence: 99%

Bladder exstrophy-epispadias complex related litigation: A legal database review

et al. 2023

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“…In the light of the above, it can be stated that, for a significative part of infant and fetal deaths, the specific pathophysiologic processes cannot be recognized, not permitting to communicate the specific cause of death to parents and to identify preventive measures (Lavezzi et al, 2019). In addition, in case of medical malpractice claims and/or inspections requested by prosecutors, the impossibility to identify a certain -or at least probable -cause of infant/fetal death is a significant limitation for forensic operators (Kettner et al, 2014;Lupariello et al, 2019;Lupariello et al, 2021;Rutty et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Micro-CT to study and reconstruct fetal and infant coronary arteries: a pilot study on a novel post-mortem technique

Lupariello¹,

Genova²,

Mussano³

et al. 2022

EJA

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For a significant part of infant and fetal deaths, specific pathophysiologic processes cannot be recognized. Thus, the scientific community is called to identify novel post-mortem diagnostic tools. This manuscript proposes the results of a pilot study which reports a novel post-mortem technique to study and reconstruct fetal/ infant coronary arteries. The study included human fetuses characterized by the absence of macroscopic cardiac abnormalities at postmortem in situ examination. For the study of fetal hearts, it was used a curing radiopaque silicone rubber compound (which solidified after injection in the coronary arteries) and an X-Ray microtomography (micro-CT). After micro- CT scans, coronary arteries’ branches were reconstructed throughout a specific software. At injection, it was possible to macroscopically evaluate coronary arteries’ perfusion. The analysis of the three-dimensional reconstructions highlighted that the aforementioned compound reached deep branches too. This approach can be considered a novel post-mortem technique for fetal/infant hearts. Nevertheless, the manuscript also discussed the following limitations: in some spots, coronary arteries’ reconstruction appeared interrupted; the compound also perfused parts of internal cardiac chambers. Until now, in the literature there are not methods that allow study with reconstruction of fetal/infant coronary arteries throughout micro-CT. The present paper pointed out the first indications for the application of this technique in human samples.

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“…According to the Center for Disease Control and Prevention (CDC), each year about 3,400 In the light of the above, it can be stated that, for a significative part of infant and fetal deaths, the specific pathophysiologic processes cannot be recognized, not permitting to communicate the specific cause of death to parents and to identify preventive measures (Lavezzi et al, 2019). In addition, in case of medical malpractice claims and/or inspections requested by prosecutors, the impossibility to identify a certain -or at least probable -cause of infant/fetal death is a significant limitation for forensic operators (Kettner et al, 2014;Lupariello et al, 2019;Lupariello et al, 2021;Rutty et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

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2022

EJA

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Teeth are a valuable source of information for studies regarding past human populations in archaeological and forensic contexts. In dental anthropology, the linear measurements of tooth crowns are used for assessing morphological variability and sexual dimorphism in both modern and past human populations. The aim of this research is to evaluate the M2 molar crown variability in archaeological human populations from Prehistory (Chalcolithic and Bronze Age, ~ 5000-1150 BCE) and Middle Ages (13 th -17 th centuries) discovered in sites from North-Eastern Romania. The objectives of this study emphasize on the diachronic comparison of the M2 molar crown variables between prehistoric and medieval samples (1), and the assessment of sexual dimorphism expression (2). The two crown measurements, mesio-distal (MD) and bucco-lingual (BL) diameters, were performed using ImageJ software on occlusal digital images acquired stereo-microscopically. The crown index (CI), crown area (CA) and the sexual dimorphism index (SDI), along with the two linear measurements, were subjected to univariate and multivariate statistical analysis.Our results show that the variation coefficient (CV) differs for the MD variable in the female upper M2 molars, being higher in the medieval sample than the prehistoric one; also, a higher variability is remarked for the mandibular molar in the medieval sample than in prehistoric one. In females, the MD and CA variables for mandibular M2 molars and the BL and CA for maxillary molars showed significant statistical differences between the medieval and prehistoric mandibular teeth, with higher values for the exemplar from Middle Ages. Similar result was obtained in males, for the CA variable in the upper M2 molars. In our study, the sexual dimorphism manifested at the M2 crown molar was highlighted in the prehistoric sample, though less in the medieval one.

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Causes of death shortly after delivery and medical malpractice claims in congenital high airway obstruction syndrome: Review of the literature

Cited by 8 publications

References 34 publications

Bladder exstrophy-epispadias complex related litigation: A legal database review

Bladder exstrophy-epispadias complex related litigation: A legal database review

Micro-CT to study and reconstruct fetal and infant coronary arteries: a pilot study on a novel post-mortem technique

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