Causes of Death in Treated Hypertensive Patients

Smirk, Horace; Hodge, J. V.

doi:10.1136/bmj.2.5367.1221

Cited by 47 publications

(5 citation statements)

References 6 publications

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“…In our study, no definite change between treated and control groups was recognized, though cerebral death seemed to be appreciably higher in treated group. Changing proportion of causes of death from treatment has been reported recently.15), 20) It has been pointed out in Study I that most of cerebral deaths in Group B developed within a relatively short period after the discontinuing (iii). A warning was made in several reports1)-3) as to a danger of early death particularly of cerebral origin due to abrupt discontinuing of intensive treatment.…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of Prolonged Antihypertensive Treatment on Survival of Patients with Essential Hypertension

et al. 1964

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Section: Methodsmentioning

confidence: 99%

Effectiveness of Prolonged Antihypertensive Treatment on Survival of Patients with Essential Hypertension

et al. 1964

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“…Hypotensive Drugs andPeptic Ulcer Hypotonus in the gastrointestinal tract is a recognized side-effect of many of the drugs used in the treatment of hypertension, especially the ganglionblocking agents. A study of mortality and morbidity figures in several series of cases of hypertension under prolonged treatment by hypotensive drugs shows that peptic ulcer is extremely rare in these cases (Smith & Fowler 1955, Smirk 1963, Smirk & Hodge 1963. In a total of 173 deaths which occurred among approximately 700 cases attending Smirk's hypertensive clinic, no death was due to peptic ulcer (Smirk 1965, personal communication).…”

Section: Pregnancy Anidpeptic Ulcermentioning

confidence: 99%

President's Address. Muscle Spasm in the Etiology of Chronic Peptic Ulcer

Qvist

1974

Proceedings of the Royal Society of Medicine

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Motor activity and spasm were for many years regarded as factors of great importance in the genesis and symptomatology of chronic peptic ulcer. In recent times, however, the factor of myospasm has claimed far less attention, the emphasis being placed almost entirely on acidity as being of greatest significance in the etiology, symptomatology and therapy of peptic ulceration. There is little reference in current literature to the relief of muscle spasm as a factor of importance in the healing of peptic ulcer.It is suggested that motor activity is in fact an important element in the pathology and clinical features of chronic peptic ulcer. There are numerous conditions in which myospasm and peptic ulcer are associated and also some conditions of gastrointestinal hypotonia in which peptic ulcer is rarely found.

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“…Loss of tone in the alimentary tract is one of the recognised side‐effects of many of the hypotensive drugs used in hypertension, particularly the ganglion‐blocking agents. It may be of significance that a study of mortality and morbidity figures in several series of cases of hypertension under prolonged treatment by hypotensive drugs shows that peptic ulcer is almost unknown in these cases (Smirk & Hodge 1963; Smirk 1963; Smith & Fowler 1955).…”

Section: Rationale Of Conservative Surgerymentioning

confidence: 99%