Causes of death in patients undergoing liver surgery

Detroz, Bernard; Sugarbaker, Paul H.; Knol, James A.; Petrelli, Nicholas J.; Hughes, Kevin S.

doi:10.1007/978-1-4615-2604-9_20

Cited by 25 publications

(20 citation statements)

References 53 publications

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“…[108][109][110][111][112] In recent literature, the incidence is less than 10%, owing to improved preoperative assessment and intraoperative and postoperative management. 78,113 Liver failure still remains a major factor in post-hepatectomy mortality, accounting for 18% to 75% of deaths in some series, [114][115][116] and up to 60% to 100% of deaths in other series. [117][118][119] There have been in excess of 50 studies that have defined PHLF.…”

Section: Post-hepatectomy Liver Failurementioning

confidence: 99%

Complications Following Hepatectomy

Russell

2015

Surgical Oncology Clinics of North America

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Section: Post-hepatectomy Liver Failurementioning

confidence: 99%

Complications Following Hepatectomy

Russell

2015

Surgical Oncology Clinics of North America

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“…17,18 The decision to proceed with PVE was made only after careful evaluation of CT scan volumetry. PVE was performed systematically when the estimated rate of remnant functional liver parenchyma (ERRFLP) was 40% or less.…”

Section: Pvementioning

confidence: 99%

Resection of Nonresectable Liver Metastases From Colorectal Cancer After Percutaneous Portal Vein Embolization

et al. 2000

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ObjectiveTo assess the influence of preoperative portal vein embolization (PVE) on the long-term outcome of liver resection for colorectal metastases. Summary Background DataPreoperative PVE of the liver induces hypertrophy of the remnant liver and increases the safety of hepatectomy. MethodsThirty patients underwent preoperative PVE and 88 patients did not before resection of four or more liver segments. PVE was performed when the estimated rate of remnant functional liver parenchyma (ERRFLP) assessed by CT scan volumetry was less than 40%. ResultsPVE was feasible in all patients. There were no deaths. The complication rate was 3%. The post-PVE ERRFLP was significantly increased compared with the pre-PVE value. Liver resection was performed after PVE in 19 patients (63%), with surgical death and complication rates of 4% and 7% respectively. PVE increased the number of resections of more than four segments by 19% (17/88). Actuarial survival rates after hepatectomy with or without previous PVE were comparable: 81%, 67%, and 40% versus 88%, 61%, and 38% at 1, 3, and 5 years respectively.

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“…However, depending on geographic location, 50 -80% of patients with HCC have associated cirrhosis [12]. Surgery of the cirrhotic liver carries a high risk, and, according to two recent reviews [3,13], liver failure is the major cause of death after hepatectomy for HCC. Thus, it is of paramount importance to estimate liver function preoperatively and to predict the postoperative remaining functional liver parenchyma.…”

Section: Discussionmentioning

confidence: 99%