Causes of death in five hundred thirty-three fatal cases of toxemia of pregnancy

Donnelly, James F.; Lock, Frank R.

doi:10.1016/0002-9378(54)90477-9

Cited by 38 publications

(11 citation statements)

References 12 publications

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“…Between 5 and 10% of patients with eclampsia die from the disease process. Cerebral dysfunction, renal failure and pulmonary oedema are the most common terminal events (Donnelly et al 1954).…”

Section: Discussionmentioning

confidence: 99%

Active Management of the Unconscious Eclamptic Patient

Richards

Moodley

Graham

et al. 1987

Obstetrical & Gynecological Survey

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Of the many complications which may develop after eclamptic seizures, prolonged unconsciousness is one of the most difficult for obstetricians to manage as the pathophysiology of this condition remains largely unknown. Computed axial tomography (CT scan) was performed on 20 unconscious eclamptic patients, and autopsy was obtained on an additional two patients. Changes compatable with cerebral oedema were demonstrated in 75% of patients; cerebral haemorrhage occurred in 9%. A programme of intensive neurological management aimed at optimizing cerebral perfusion and controlling intracranial pressure is outlined. We have reduced the mortality rate for unconscious eclamptic patients from 50% to 17% in our institution.

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Section: Discussionmentioning

confidence: 99%

Active Management of the Unconscious Eclamptic Patient

Richards

Moodley

Graham

et al. 1987

Obstetrical & Gynecological Survey

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“…[20,22] In addition, there is a two-fold increase in risk of maternal mortality in triplets over singleton pregnancies .Many studies have reported about the increased risk of pulmonary edema in triplet pregnancy. [1,2,3,11,15] .Sudden onset of breathlessness and cough are the predominant symptoms of pulmonary edema. These symptoms may at times be attributed to over distended uterus in multifetal gestation.…”

Section: Discussionmentioning

confidence: 99%

“…Although an uncommon event in pregnancy, it is associated with an increased risk of maternal and fetal morbidity and mortality. [1] Several risk factors have been identified: preeclampsia or Eclampsia [1][2][3] use of tocolytic therapy, [4][5][6][7][8][9][10] severe infection, [3,8,9] cardiac disease, [11] iatrogenic fluid overload [5,11] and multiple gestation. Furthermore, the physiologic changes associated with pregnancy may predispose the pregnant patient to pulmonary edema [12][13][14][15] …”

Section: Introductionmentioning

confidence: 99%

Acute pulmonary edema complicating triplet pregnancy-A Case report

Bangal¹

2012

iosrphr

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The incidence of triplet pregnancies is on rise due to increase in the use of fertility enhancing drugs for assisted reproductive techniques .Triplet pregnancies are associated with adverse maternal and fetal outcome .There is many fold increase in the risk to the pregnant woman due to associated medical complications like anemia and hypertension. Acute pulmonary edema is rare but life threatening complication of triplet pregnancy. We report a case of primigravida with 32 weeks of triplet pregnancy, who developed acute pulmonary edema, secondary to pregnancy induced hypertension .She was delivered by emergency caesarean section after treatment of pulmonary edema. All three premature low birth weight babies survived after cesarean birth .Patient required admission in intensive care unit for three days after caesarean section .Patient was discharged on eighteenth postoperative day with three fully breastfed babies.

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“…In eclampsia, however, subarachnoid haemorrhage is a recognized complication (Donnelly and Lock, 1954). The figures for incidence vary from 1 in 2,000 (Cannell and Bottrell, 1956), to 1 in 11,000 pregnancies (O'Leary et al, 1962); the variation would appear to be an expression of the observer's interests rather than social or racial factors.…”

Section: Discussionmentioning

confidence: 99%

Pregnancy, subarachnoid haemorrhage, and the intravascular coagulation syndrome

Heron

Hutchinson

Boyd

et al. 1974

Journal of Neurology, Neurosurgery & Psychiatry

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SYNOPSIS Two patients are described who developed subarachnoid haemorrhage during pregnancy and the puerperium. In both patients there was clinical, haematological, histological, and renal angiographic evidence of the intravascular coagulation syndrome. No source of intracranial bleeding was demonstrated by bilateral carotid angiography in either patient. We suggest that the subarachnoid haemorrhage was a result of the intravascular coagulation syndrome in both patients.

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Causes of death in five hundred thirty-three fatal cases of toxemia of pregnancy

Cited by 38 publications

References 12 publications

Active Management of the Unconscious Eclamptic Patient

Active Management of the Unconscious Eclamptic Patient

Acute pulmonary edema complicating triplet pregnancy-A Case report

Pregnancy, subarachnoid haemorrhage, and the intravascular coagulation syndrome

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