Causes of death and associated factors among patients with non-insulin-dependent diabetes mellitus in Taipei, Taiwan

Chen, K. T.; Chen, C. J.; Fuh, Martin Mao-Tsu; Narayan, K.M. Venkat

doi:10.1016/s0168-8227(98)00126-0

Cited by 16 publications

(13 citation statements)

References 46 publications

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“…Studies about the relationship between proteinuria and mortality among non-whites are also limited. 8,10 In this study, we describe the relationship between proteinuria at baseline and death from cardiovascular disease in a nationally representative cohort of the Japanese population. …”

mentioning

confidence: 99%

Proteinuria is a Prognostic Marker for Cardiovascular Mortality: NIPPON DATA 80, 1980-1999

Tanihara

Hayakawa

Oki

et al. 2005

Journal of Epidemiology

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Proteinuria or urinary albumin has been considered to be a prognostic marker for patients with non-insulin-dependent diabetes mellitus 1-14 and those with hypertension 10,15-18 or acute myocardial infarction. 19 However, in general population, knowledge about the relationship between proteinuria and mortality is limited. 14 Proteinuria has been a predictor of mortality in subjects aged 65-79 years 20 but not among those 80 years and older. 21 Urinary albumin is related to risk factors for cardiovascular diseases, 15,22 but in only a few studies has diabetes mellitus or the history of renal diseases been assessed. 23 In addition, most of these studies have been conducted in European countries and in the United States. Studies about the relationship between proteinuria and mortality among non-whites are also limited. 8,10 In this study, we describe the relationship between proteinuria at baseline and death from cardiovascular disease in a nationally representative cohort of the Japanese population.

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confidence: 99%

Proteinuria is a Prognostic Marker for Cardiovascular Mortality: NIPPON DATA 80, 1980-1999

Tanihara

Hayakawa

Oki

et al. 2005

Journal of Epidemiology

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“…Smoking status was considered to be non-reliable data for this cohort. It has been reported as a mortality risk factor in some investigations (1,21,25), but not in others (4,6,8,26). Information on metabolic control provided by HbA 1c levels probably was, at least partially, provided by mean fasting glycemia levels obtained during the first year of follow-up.…”

Section: Discussionmentioning

confidence: 94%

“…Various studies have shown a better survival in non-proteinuric type 2 diabetic patients. Nevertheless, most of these studies are based on simple qualitative dipstick or precipitation screening tests (1,6,7,(9)(10)(11)18) or on urinary protein concentration from a morning spot (19). In the present study, the measurement of 24-h urinary protein excretion was assessed on at least three different occasions, whenever possible.…”

Section: Discussionmentioning

confidence: 99%

“…Several prospective studies have reported that abnormal proteinuria or albuminuria are predictors of all-cause and cardiovascular mortality in patients with diabetes (1)(2)(3)(4)(5)(6)(7)(8), and also in the non-diabetic population (9)(10)(11). However, most longitudinal studies on proteinuria and mortality were conducted in European countries (1)(2)(3)(4)(5), in the USA (7,9,11) and some in Asia (6,10).…”

Section: Introductionmentioning

confidence: 99%

“…However, most longitudinal studies on proteinuria and mortality were conducted in European countries (1)(2)(3)(4)(5), in the USA (7,9,11) and some in Asia (6,10). Also, there is variability in the extent of the increase in mortality associated with proteinuria among different geographic locations.…”

Section: Introductionmentioning

confidence: 99%

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Gross proteinuria is a strong risk predictor for cardiovascular mortality in Brazilian type 2 diabetic patients

Cardoso¹,

Salles²

2008

Braz J Med Biol Res

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Increased proteinuria is recognized as a risk predictor for all-cause and cardiovascular mortality in diabetic patients; however, no study has evaluated these relationships in Brazilian patients. The aim of this study was to investigate the prognostic value of gross proteinuria for all-cause and cardiovascular mortalities and for cardiovascular morbidity in a cohort study of 471 type 2 diabetic individuals followed for up to 7 years. Several clinical, laboratory and electrocardiographic variables were obtained at baseline. The relative risks for all-cause, cardiovascular and cardiac mortalities and for cardiovascular and cardiac events associated with the presence of overt proteinuria (>0.5 g/24 h) were assessed by Kaplan-Meier survival curves and by multivariate Cox regression model. During a median follow-up of 57 months (range 2-84 months), 121 patients (25.7%) died, 44 from cardiovascular and 30 from cardiac causes, and 106 fatal or non-fatal cardiovascular events occurred. Gross proteinuria was an independent risk predictor of all-cause, cardiovascular and cardiac mortalities and of cardiovascular morbidity with adjusted relative risks ranging from 1.96 to 4.38 for the different endpoints. This increased risk remained significant after exclusion of patients with prior cardiovascular disease at baseline from the multivariate analysis. In conclusion, gross proteinuria was a strong predictor of all-cause, cardiovascular and cardiac mortalities and also of cardiovascular morbidity in a Brazilian cohort of type 2 diabetic patients. Intervention studies are necessary to determine whether the reduction of proteinuria can decrease morbidity and mortality of type 2 diabetes in Brazil.

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Community-Acquired Spontaneous Bacterial Meningitis in Adult Diabetic Patients: An Analysis of Clinical Characteristics and Prognostic Factors

Huang¹,

Lu²,

Chang

et al. 2002

Infection

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Causes of death and associated factors among patients with non-insulin-dependent diabetes mellitus in Taipei, Taiwan

Cited by 16 publications

References 46 publications

Proteinuria is a Prognostic Marker for Cardiovascular Mortality: NIPPON DATA 80, 1980-1999

Proteinuria is a Prognostic Marker for Cardiovascular Mortality: NIPPON DATA 80, 1980-1999

Gross proteinuria is a strong risk predictor for cardiovascular mortality in Brazilian type 2 diabetic patients

Community-Acquired Spontaneous Bacterial Meningitis in Adult Diabetic Patients: An Analysis of Clinical Characteristics and Prognostic Factors

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