Causal relationships between sleep duration and risk of breast tumors: A two-sample bi-directional Mendelian randomization study
Litong Shao,
Dan Zhao,
Jing Ji
et al.
Abstract:Background Previous observational studies reported that sleep traits were associated with breast tumors. However, the causal relationship between sleep duration and breast tumors is not clear.
Methods We performed a two-sample bi-directional Mendelian randomization (MR) analysis with publicly available GWAS summary statistics to detect the causal relationship between genetically predicted sleep duration and the risk of breast tumors, including breast cancer (estrogen receptor (ER)+/ER-, human epidermal growth … Show more
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