Causal effects of neuroticism on postpartum depression: a bidirectional mendelian randomization study
Qianying Hu,
Jianhua Chen,
Jingjing Ma
et al.
Abstract:Purpose
Postpartum depression (PPD) brings adverse and serious consequences to both new parents and newborns. Neuroticism affects PPD, which remains controversial for confounding factors and reverse causality in cross-sectional research. Therefore, mendelian randomization (MR) study has been adopted to investigate their causal relationship.
Methods
This study utilized large-scale genome-wide association study genetic pooled data from three major databases:… Show more
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