Causal effects of gut microbiota on ARDS: a two-sample Mendelian randomization study
Dongliang Yang,
Hongyan Guo,
Rui Xia
et al.
Abstract:Background A growing number of studies showed that altered gut microbiota is associated with the pathogenesis of ARDS. However, the potential causal relationship remained unclear. Herein, we adopted a two-sample Mendelian randomization (MR) study to investigate the causal relationship between gut microbiota and ARDS.
Methods We used publicly available genome-wide association study (GWAS) summary data to perform MR analysis. Gut microbiota GWAS were obtained from the MiBioGen study and summary-level GWAS datase… Show more
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