Causal effects of autoimmune diseases on temporomandibular disorders and the mediating pathways: a Mendelian randomization study
Xin Chen,
Zheng Cheng,
Junyu Xu
et al.
Abstract:BackgroundThe role of autoimmune diseases (ADs) in temporomandibular disorders (TMDs) has been emphasized in observational studies. However, whether the causation exists is unclear, and controversy remains about which specific disorder is destructive in TMDs. This Mendelian randomization (MR) study aims to estimate the causal effect of common ADs on TMDs.MethodsGenetic data from published genome-wide association studies for fourteen common ADs, specifically multiple sclerosis (MS, N = 15,283), ankylosing spond… Show more
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